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Year Number of Results
1997 1
1999 1
2019 4
2020 287
2021 2713
2022 429
2023 200
2024 235
2025 34

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3,277 results

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Page 1
EMT-associated microRNAs and their roles in cancer stemness and drug resistance.
Pan G, Liu Y, Shang L, Zhou F, Yang S. Pan G, et al. Cancer Commun (Lond). 2021 Mar;41(3):199-217. doi: 10.1002/cac2.12138. Epub 2021 Jan 27. Cancer Commun (Lond). 2021. PMID: 33506604 Free PMC article. Review.
In this review, we preliminarily looked into the various roles that the EMT-associated miRNAs play in the stem-like nature of malignant cells. Then, we reviewed the interaction between EMT-associated miRNAs and the drug-resistant complex signaling pathways of multiple canc …
In this review, we preliminarily looked into the various roles that the EMT-associated miRNAs play in the stem-like nature of maligna …
Twenty years of plant genome sequencing: achievements and challenges.
Sun Y, Shang L, Zhu QH, Fan L, Guo L. Sun Y, et al. Trends Plant Sci. 2022 Apr;27(4):391-401. doi: 10.1016/j.tplants.2021.10.006. Epub 2021 Nov 12. Trends Plant Sci. 2022. PMID: 34782248 Review.
Importantly, multiple reference-level genomes have been generated for the major crops and their progenitors, enabling the creation of pan-genomes and exploration of domestication history and natural variations that can be adopted by modern crop breeding. We summariz …
Importantly, multiple reference-level genomes have been generated for the major crops and their progenitors, enabling the creation of pan
Natural compounds modulate the autophagy with potential implication of stroke.
Ahsan A, Liu M, Zheng Y, Yan W, Pan L, Li Y, Ma S, Zhang X, Cao M, Wu Z, Hu W, Chen Z, Zhang X. Ahsan A, et al. Acta Pharm Sin B. 2021 Jul;11(7):1708-1720. doi: 10.1016/j.apsb.2020.10.018. Epub 2020 Oct 29. Acta Pharm Sin B. 2021. PMID: 34386317 Free PMC article. Review.
However, under certain circumstances, autophagy activation induces cell death and aggravates ischemic brain injury. Diverse naturally derived compounds have been found to modulate autophagy and exert neuroprotection against stroke. In the present work, we have reviewed rec …
However, under certain circumstances, autophagy activation induces cell death and aggravates ischemic brain injury. Diverse naturally
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Kaptein SJF, Goethals O, Kiemel D, Marchand A, Kesteleyn B, Bonfanti JF, Bardiot D, Stoops B, Jonckers THM, Dallmeier K, Geluykens P, Thys K, Crabbe M, Chatel-Chaix L, Münster M, Querat G, Touret F, de Lamballerie X, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Van Loock M, Neyts J. Kaptein SJF, et al. Nature. 2021 Oct;598(7881):504-509. doi: 10.1038/s41586-021-03990-6. Epub 2021 Oct 6. Nature. 2021. PMID: 34616043 Free article.
Here, we describe a highly potent dengue virus inhibitor (JNJ-A07) that exerts nanomolar to picomolar activity against a panel of 21 clinical isolates that represent the natural genetic diversity of known genotypes and serotypes. The molecule has a high barrier to resistan …
Here, we describe a highly potent dengue virus inhibitor (JNJ-A07) that exerts nanomolar to picomolar activity against a panel of 21 clinica …
Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection.
Barber AE, Sae-Ong T, Kang K, Seelbinder B, Li J, Walther G, Panagiotou G, Kurzai O. Barber AE, et al. Nat Microbiol. 2021 Dec;6(12):1526-1536. doi: 10.1038/s41564-021-00993-x. Epub 2021 Nov 24. Nat Microbiol. 2021. PMID: 34819642
Despite an estimated annual occurrence of more than 300,000 cases of invasive disease worldwide, a comprehensive survey of the genomic diversity present in A. fumigatus-including the relationship between clinical and environmental isolates and how this genetic diversity contribut …
Despite an estimated annual occurrence of more than 300,000 cases of invasive disease worldwide, a comprehensive survey of the genomic diver …
Intranasal vaccination.
Fehervari Z. Fehervari Z. Nat Immunol. 2021 Sep;22(9):1071. doi: 10.1038/s41590-021-01016-x. Nat Immunol. 2021. PMID: 34429547 No abstract available.
A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint.
Zhou X, Du J, Liu C, Zeng H, Chen Y, Liu L, Wu D. Zhou X, et al. Front Immunol. 2021 Jul 9;12:688215. doi: 10.3389/fimmu.2021.688215. eCollection 2021. Front Immunol. 2021. PMID: 34305920 Free PMC article.
We evaluated the role of CD161 using The Cancer Genome Atlas (TCGA) Pan-Cancer Data. METHODS: CD161 expression was analysed using RNAseq data from TCGA and the Genotype-Tissue Expression (GTEx) database. ...FUNDING: This work was supported by the National Nature Sci …
We evaluated the role of CD161 using The Cancer Genome Atlas (TCGA) Pan-Cancer Data. METHODS: CD161 expression was analysed using RNA …
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Wang Z, Su G, Dai Z, Meng M, Zhang H, Fan F, Liu Z, Zhang L, Weygant N, He F, Fang N, Zhang L, Cheng Q. Wang Z, et al. Cell Prolif. 2021 Mar;54(3):e12988. doi: 10.1111/cpr.12988. Epub 2021 Jan 13. Cell Prolif. 2021. PMID: 33442944 Free PMC article.
The risk model can predict glioma survival outcome, and this model can also be applied to pan-cancer....
The risk model can predict glioma survival outcome, and this model can also be applied to pan-cancer....
Origins of modern human ancestry.
Bergström A, Stringer C, Hajdinjak M, Scerri EML, Skoglund P. Bergström A, et al. Nature. 2021 Feb;590(7845):229-237. doi: 10.1038/s41586-021-03244-5. Epub 2021 Feb 10. Nature. 2021. PMID: 33568824 Review.
Cardio-oncology: rationale, aims and future directions.
Pan J, Garza F, Lyon AR. Pan J, et al. Curr Opin Support Palliat Care. 2021 Jun 1;15(2):134-140. doi: 10.1097/SPC.0000000000000544. Curr Opin Support Palliat Care. 2021. PMID: 33605633 Review.
This article explains to the reader what cardio-oncology services provide and the nature of cardiovascular problems caused by the growing array of modern cancer therapies. ...
This article explains to the reader what cardio-oncology services provide and the nature of cardiovascular problems caused by the gro …
3,277 results