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11 results
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Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.
Ang JE, Pandher R, Ang JC, Asad YJ, Henley AT, Valenti M, Box G, de Haven Brandon A, Baird RD, Friedman L, Derynck M, Vanhaesebroeck B, Eccles SA, Kaye SB, Workman P, de Bono JS, Raynaud FI. Ang JE, et al. Among authors: pandher r. Mol Cancer Ther. 2016 Jun;15(6):1412-24. doi: 10.1158/1535-7163.MCT-15-0815. Epub 2016 Apr 5. Mol Cancer Ther. 2016. PMID: 27048952 Free PMC article. Clinical Trial.
Site-selective hole burning in Eu3+:Y2SiO5.
Pandher RS, Jackson A, Davis A, Reddy BR. Pandher RS, et al. Appl Opt. 1999 Sep 10;38(26):5662-5. doi: 10.1364/ao.38.005662. Appl Opt. 1999. PMID: 18324078
Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma.
Xiao L, Somers K, Murray JE, Pandher R, Karsa M, Ronca E, Bongers A, Terry R, Ehteda A, Gamble LD, Issaeva N, Leonova KI, O'Connor A, Mayoh C, Venkat P, Quek H, Brand J, Kusuma FK, Pettitt JA, Mosmann E, Kearns A, Eden G, Alfred S, Allan S, Zhai L, Kamili A, Gifford AJ, Carter DR, Henderson MJ, Fletcher JI, Marshall G, Johnstone RW, Cesare AJ, Ziegler DS, Gudkov AV, Gurova KV, Norris MD, Haber M. Xiao L, et al. Among authors: pandher r. Clin Cancer Res. 2021 May 16:clincanres.2357.2020. doi: 10.1158/1078-0432.CCR-20-2357. Online ahead of print. Clin Cancer Res. 2021. PMID: 33994371
Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Ehteda A, Simon S, Franshaw L, Giorgi FM, Liu J, Joshi S, Rouaen JRC, Pang CNI, Pandher R, Mayoh C, Tang Y, Khan A, Ung C, Tolhurst O, Kankean A, Hayden E, Lehmann R, Shen S, Gopalakrishnan A, Trebilcock P, Gurova K, Gudkov AV, Norris MD, Haber M, Vittorio O, Tsoli M, Ziegler DS. Ehteda A, et al. Among authors: pandher r. Cell Rep. 2021 Apr 13;35(2):108994. doi: 10.1016/j.celrep.2021.108994. Cell Rep. 2021. PMID: 33852836
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.
Khan A, Gamble LD, Upton DH, Ung C, Yu DMT, Ehteda A, Pandher R, Mayoh C, Hébert S, Jabado N, Kleinman CL, Burns MR, Norris MD, Haber M, Tsoli M, Ziegler DS. Khan A, et al. Among authors: pandher r. Nat Commun. 2021 Feb 12;12(1):971. doi: 10.1038/s41467-021-20896-z. Nat Commun. 2021. PMID: 33579942 Free PMC article.
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.
Somers K, Wen VW, Middlemiss SMC, Osborne B, Forgham H, Jung M, Karsa M, Clifton M, Bongers A, Gao J, Mayoh C, Raoufi-Rad N, Kusnadi EP, Hannan KM, Scott DA, Kwek A, Liu B, Flemming C, Chudakova DA, Pandher R, Failes TW, Lim J, Angeli A, Osterman AL, Imamura T, Kees UR, Supuran CT, Pearson RB, Hannan RD, Davis TP, McCarroll J, Kavallaris M, Turner N, Gudkov AV, Haber M, Norris MD, Henderson MJ. Somers K, et al. Among authors: pandher r. Oncogene. 2019 May;38(20):3824-3842. doi: 10.1038/s41388-018-0666-5. Epub 2019 Jan 22. Oncogene. 2019. PMID: 30670779 Free PMC article.
Steady two-layer gravity-driven thin-film flow.
Alba K, Khayat RE, Pandher RS. Alba K, et al. Among authors: pandher rs. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 May;77(5 Pt 2):056304. doi: 10.1103/PhysRevE.77.056304. Epub 2008 May 8. Phys Rev E Stat Nonlin Soft Matter Phys. 2008. PMID: 18643158
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