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Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties.
J Med Chem. 2003 May 22;46(11):2110-6. doi: 10.1021/jm020329q.
J Med Chem. 2003.
PMID: 12747783
C-3 Amido-indole cannabinoid receptor modulators.
Hynes J Jr, Leftheris K, Wu H, Pandit C, Chen P, Norris DJ, Chen BC, Zhao R, Kiener PA, Chen X, Turk LA, Patil-Koota V, Gillooly KM, Shuster DJ, McIntyre KW.
Hynes J Jr, et al.
Bioorg Med Chem Lett. 2002 Sep 2;12(17):2399-402. doi: 10.1016/s0960-894x(02)00466-3.
Bioorg Med Chem Lett. 2002.
PMID: 12161142
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Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles.
Arienti KL, Brunmark A, Axe FU, McClure K, Lee A, Blevitt J, Neff DK, Huang L, Crawford S, Pandit CR, Karlsson L, Breitenbucher JG.
Arienti KL, et al. Among authors: pandit cr.
J Med Chem. 2005 Mar 24;48(6):1873-85. doi: 10.1021/jm0495935.
J Med Chem. 2005.
PMID: 15771432
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Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.
Letavic MA, Aluisio L, Apodaca R, Bajpai M, Barbier AJ, Bonneville A, Bonaventure P, Carruthers NI, Dugovic C, Fraser IC, Kramer ML, Lord B, Lovenberg TW, Li LY, Ly KS, Mcallister H, Mani NS, Morton KL, Ndifor A, Nepomuceno SD, Pandit CR, Sands SB, Shah CR, Shelton JE, Snook SS, Swanson DM, Xiao W.
Letavic MA, et al. Among authors: pandit cr.
ACS Med Chem Lett. 2015 Mar 13;6(4):450-4. doi: 10.1021/ml5005156. eCollection 2015 Apr 9.
ACS Med Chem Lett. 2015.
PMID: 25893048
Free PMC article.
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Practical and scalable synthesis of a selective CCK1 receptor antagonist.
Mapes CM, Mani NS, Deng X, Pandit CR, McClure KJ, Pippel MC, Sehon CA, Gomez L, Shinde S, Breitenbucher JG, Jones TK.
Mapes CM, et al. Among authors: pandit cr.
J Org Chem. 2010 Nov 19;75(22):7950-3. doi: 10.1021/jo1017684. Epub 2010 Oct 27.
J Org Chem. 2010.
PMID: 20977279
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Role of interferon-γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice.
McDermott AJ, Falkowski NR, McDonald RA, Frank CR, Pandit CR, Young VB, Huffnagle GB.
McDermott AJ, et al. Among authors: pandit cr.
Immunology. 2017 Apr;150(4):468-477. doi: 10.1111/imm.12700. Epub 2017 Jan 30.
Immunology. 2017.
PMID: 27995603
Free PMC article.
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Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice.
McDermott AJ, Falkowski NR, McDonald RA, Pandit CR, Young VB, Huffnagle GB.
McDermott AJ, et al. Among authors: pandit cr.
Immunology. 2016 Jan;147(1):114-24. doi: 10.1111/imm.12545. Epub 2015 Dec 2.
Immunology. 2016.
PMID: 26455347
Free PMC article.
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