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The functions and regulation of the PTEN tumour suppressor: new modes and prospects.
Lee YR, Chen M, Pandolfi PP. Lee YR, et al. Nat Rev Mol Cell Biol. 2018 Sep;19(9):547-562. doi: 10.1038/s41580-018-0015-0. Nat Rev Mol Cell Biol. 2018. PMID: 29858604 Review.
Pten is essential for embryonic development and tumour suppression.
Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP. Di Cristofano A, et al. Nat Genet. 1998 Aug;19(4):348-55. doi: 10.1038/1235. Nat Genet. 1998. PMID: 9697695
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. Lee JO, et al. Cell. 1999 Oct 29;99(3):323-34. doi: 10.1016/s0092-8674(00)81663-3. Cell. 1999. PMID: 10555148
The multiple roles of PTEN in tumor suppression.
Di Cristofano A, Pandolfi PP. Di Cristofano A, et al. Cell. 2000 Feb 18;100(4):387-90. doi: 10.1016/s0092-8674(00)80674-1. Cell. 2000. PMID: 10693755 Review. No abstract available.
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse.
Di Cristofano A, De Acetis M, Koff A, Cordon-Cardo C, Pandolfi PP. Di Cristofano A, et al. Nat Genet. 2001 Feb;27(2):222-4. doi: 10.1038/84879. Nat Genet. 2001. PMID: 11175795
SUMO-1 protease-1 regulates gene transcription through PML.
Best JL, Ganiatsas S, Agarwal S, Changou A, Salomoni P, Shirihai O, Meluh PB, Pandolfi PP, Zon LI. Best JL, et al. Mol Cell. 2002 Oct;10(4):843-55. doi: 10.1016/s1097-2765(02)00699-8. Mol Cell. 2002. PMID: 12419228
Does the ribosome translate cancer?
Ruggero D, Pandolfi PP. Ruggero D, et al. Nat Rev Cancer. 2003 Mar;3(3):179-92. doi: 10.1038/nrc1015. Nat Rev Cancer. 2003. PMID: 12612653 Review.
PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP. Bernardi R, et al. Nat Cell Biol. 2004 Jul;6(7):665-72. doi: 10.1038/ncb1147. Epub 2004 Jun 13. Nat Cell Biol. 2004. PMID: 15195100
Role of nucleophosmin in embryonic development and tumorigenesis.
Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K, Pandolfi PP. Grisendi S, et al. Nature. 2005 Sep 1;437(7055):147-53. doi: 10.1038/nature03915. Epub 2005 Jul 6. Nature. 2005. PMID: 16007073
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Chen Z, et al. Nature. 2005 Aug 4;436(7051):725-30. doi: 10.1038/nature03918. Nature. 2005. PMID: 16079851 Free PMC article.
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