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1Alpha,25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo.
Chow EC, Durk MR, Cummins CL, Pang KS. Chow EC, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2011 Jun;337(3):846-59. doi: 10.1124/jpet.111.179101. Epub 2011 Mar 18. J Pharmacol Exp Ther. 2011. PMID: 21421739
Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.
Meng LJ, Wang P, Wolkoff AW, Kim RB, Tirona RG, Hofmann AF, Pang KS. Meng LJ, et al. Among authors: pang ks. Hepatology. 2002 May;35(5):1031-40. doi: 10.1053/jhep.2002.32667. Hepatology. 2002. PMID: 11981753
A catenary model to study transport and conjugation of baicalein, a bioactive flavonoid, in the Caco-2 cell monolayer: demonstration of substrate inhibition.
Sun H, Zhang L, Chow EC, Lin G, Zuo Z, Pang KS. Sun H, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2008 Jul;326(1):117-26. doi: 10.1124/jpet.108.137463. Epub 2008 Apr 2. J Pharmacol Exp Ther. 2008. PMID: 18385448
Increased estrogen sulfation of estradiol 17beta-D-glucuronide in metastatic tumor rat livers.
Sun H, Liu L, Pang KS. Sun H, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2006 Nov;319(2):818-31. doi: 10.1124/jpet.106.108860. Epub 2006 Aug 8. J Pharmacol Exp Ther. 2006. PMID: 16895976
Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers.
Liu L, Cui Y, Chung AY, Shitara Y, Sugiyama Y, Keppler D, Pang KS. Liu L, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2006 Jul;318(1):395-402. doi: 10.1124/jpet.106.103390. Epub 2006 Apr 20. J Pharmacol Exp Ther. 2006. PMID: 16627748
Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1.
Chang C, Pang KS, Swaan PW, Ekins S. Chang C, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2005 Aug;314(2):533-41. doi: 10.1124/jpet.104.082370. Epub 2005 Apr 21. J Pharmacol Exp Ther. 2005. PMID: 15845861
Moment analysis of metabolic heterogeneity: conjugation of benzoate with glycine in rat liver studied by multiple indicator dilution technique.
Schwab AJ, Tao L, Kang M, Meng L, Pang KS. Schwab AJ, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2003 Apr;305(1):279-89. doi: 10.1124/jpet.102.044024. J Pharmacol Exp Ther. 2003. PMID: 12649380
Vascular binding, blood flow, transporter, and enzyme interactions on the processing of digoxin in rat liver.
Liu L, Mak E, Tirona RG, Tan E, Novikoff PM, Wang P, Wolkoff AW, Pang KS. Liu L, et al. Among authors: pang ks. J Pharmacol Exp Ther. 2005 Oct;315(1):433-48. doi: 10.1124/jpet.105.088039. Epub 2005 Jun 30. J Pharmacol Exp Ther. 2005. PMID: 15994370
Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.
Yang QJ, Fan J, Chen S, Liu L, Sun H, Pang KS. Yang QJ, et al. Among authors: pang ks. Drug Metab Dispos. 2016 Jul;44(7):1123-38. doi: 10.1124/dmd.116.069542. Epub 2016 Apr 20. Drug Metab Dispos. 2016. PMID: 27098743
1α,25-Dihydroxyvitamin D3 reduces cerebral amyloid-β accumulation and improves cognition in mouse models of Alzheimer's disease.
Durk MR, Han K, Chow EC, Ahrens R, Henderson JT, Fraser PE, Pang KS. Durk MR, et al. Among authors: pang ks. J Neurosci. 2014 May 21;34(21):7091-101. doi: 10.1523/JNEUROSCI.2711-13.2014. J Neurosci. 2014. PMID: 24849345 Free PMC article.
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