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A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.
Pang T, Wang YJ, Gao YX, Xu Y, Li Q, Zhou YB, Xu L, Huang ZJ, Liao H, Zhang LY, Gao JR, Ye Q, Li J. Pang T, et al. Acta Pharmacol Sin. 2016 Jun;37(6):741-52. doi: 10.1038/aps.2016.3. Epub 2016 Apr 25. Acta Pharmacol Sin. 2016. PMID: 27108601 Free PMC article.
Knockdown of long noncoding RNA MEG3 impairs VEGF-stimulated endothelial sprouting angiogenesis via modulating VEGFR2 expression in human umbilical vein endothelial cells.
Ruan W, Zhao F, Zhao S, Zhang L, Shi L, Pang T. Ruan W, et al. Gene. 2018 Apr 5;649:32-39. doi: 10.1016/j.gene.2018.01.072. Epub 2018 Jan 31. Gene. 2018. PMID: 29391273
Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3β inhibitors and neuroprotective agents.
Hu Y, Ruan W, Gao A, Zhou Y, Gao L, Xu M, Gao J, Ye Q, Li J, Pang T. Hu Y, et al. Pharmazie. 2017 Dec 1;72(12):707-713. doi: 10.1691/ph.2017.7722. Pharmazie. 2017. PMID: 29441954
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.
Wang YY, Gao YX, Gao W, Xu Y, Xu YZ, Wang YJ, Chang S, Yu LG, Zhang LY, Liao H, Yang LF, Pang T, Qiu WW. Wang YY, et al. Eur J Med Chem. 2015 Oct 20;103:396-408. doi: 10.1016/j.ejmech.2015.08.057. Epub 2015 Sep 10. Eur J Med Chem. 2015. PMID: 26375352
Discovery of novel aromatase inhibitors using a homogeneous time-resolved fluorescence assay.
Ji JZ, Lao KJ, Hu J, Pang T, Jiang ZZ, Yuan HL, Miao JS, Chen X, Ning SS, Xiang H, Guo YM, Yan M, Zhang LY. Ji JZ, et al. Acta Pharmacol Sin. 2014 Aug;35(8):1082-92. doi: 10.1038/aps.2014.53. Epub 2014 Jul 21. Acta Pharmacol Sin. 2014. PMID: 25047514 Free PMC article.
Synthesis and biological evaluation of 3-benzisoxazolyl-4-indolylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3β.
Ye Q, Li M, Zhou Y, Pang T, Xu L, Cao J, Han L, Li Y, Wang W, Gao J, Li J. Ye Q, et al. Molecules. 2013 May 13;18(5):5498-516. doi: 10.3390/molecules18055498. Molecules. 2013. PMID: 23669633 Free PMC article.
Glimepiride attenuates Aβ production via suppressing BACE1 activity in cortical neurons.
Liu F, Wang Y, Yan M, Zhang L, Pang T, Liao H. Liu F, et al. Neurosci Lett. 2013 Dec 17;557 Pt B:90-4. doi: 10.1016/j.neulet.2013.10.052. Epub 2013 Oct 31. Neurosci Lett. 2013. PMID: 24184877
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