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Increased sensitivity to CD4 binding site-directed neutralization following in vitro propagation on primary lymphocytes of a neutralization-resistant human immunodeficiency virus IIIB strain isolated from an accidentally infected laboratory worker.
Beaumont T, Quakkelaar E, van Nuenen A, Pantophlet R, Schuitemaker H. Beaumont T, et al. Among authors: pantophlet r. J Virol. 2004 Jun;78(11):5651-7. doi: 10.1128/JVI.78.11.5651-5657.2004. J Virol. 2004. PMID: 15140962 Free PMC article.
Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.
Pantophlet R, Wilson IA, Burton DR. Pantophlet R, et al. J Virol. 2003 May;77(10):5889-901. doi: 10.1128/jvi.77.10.5889-5901.2003. J Virol. 2003. PMID: 12719582 Free PMC article.
In a first study, we found that four alanine substitutions on the perimeter of the so-called Phe-43 cavity of gp120 could reduce binding of weakly neutralizing CD4-binding site antibodies (R. Pantophlet, E. O. Saphire, P. Poignard, P. W. H. I. Parren, I. A. Wilson, …
In a first study, we found that four alanine substitutions on the perimeter of the so-called Phe-43 cavity of gp120 could reduce binding of …
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR. Astronomo RD, et al. Among authors: pantophlet r. J Virol. 2008 Jul;82(13):6359-68. doi: 10.1128/JVI.00293-08. Epub 2008 Apr 23. J Virol. 2008. PMID: 18434393 Free PMC article.
65 results