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Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy.
Grisendi G, Bussolari R, Cafarelli L, Petak I, Rasini V, Veronesi E, De Santis G, Spano C, Tagliazzucchi M, Barti-Juhasz H, Scarabelli L, Bambi F, Frassoldati A, Rossi G, Casali C, Morandi U, Horwitz EM, Paolucci P, Conte P, Dominici M. Grisendi G, et al. Cancer Res. 2010 May 1;70(9):3718-29. doi: 10.1158/0008-5472.CAN-09-1865. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388793
Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche.
Marino R, Otsuru S, Hofmann TJ, Olson TS, Rasini V, Veronesi E, Boyd K, Gaber MW, Martinez C, Paolucci P, Dominici M, Horwitz EM. Marino R, et al. Biol Blood Marrow Transplant. 2013 Nov;19(11):1566-73. doi: 10.1016/j.bbmt.2013.07.025. Epub 2013 Aug 2. Biol Blood Marrow Transplant. 2013. PMID: 23916672
Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.
Olson TS, Caselli A, Otsuru S, Hofmann TJ, Williams R, Paolucci P, Dominici M, Horwitz EM. Olson TS, et al. Blood. 2013 Jun 27;121(26):5238-49. doi: 10.1182/blood-2012-10-463414. Epub 2013 May 10. Blood. 2013. PMID: 23667055 Free PMC article.
IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation.
Caselli A, Olson TS, Otsuru S, Chen X, Hofmann TJ, Nah HD, Grisendi G, Paolucci P, Dominici M, Horwitz EM. Caselli A, et al. Stem Cells. 2013 Oct;31(10):2193-204. doi: 10.1002/stem.1463. Stem Cells. 2013. PMID: 23818291
Endpoints in paediatric oncology.
Paolucci P, Cioni V, Bigi E, Lucaccioni L, Cano C. Paolucci P, et al. Eur J Clin Pharmacol. 2011 May;67 Suppl 1:33-40. doi: 10.1007/s00228-010-0923-1. Epub 2010 Nov 18. Eur J Clin Pharmacol. 2011. PMID: 21085937 Review.
In vitro differentiation of human amniotic epithelial cells into insulin-producing 3D spheroids.
Okere B, Alviano F, Costa R, Quaglino D, Ricci F, Dominici M, Paolucci P, Bonsi L, Iughetti L. Okere B, et al. Int J Immunopathol Pharmacol. 2015 Sep;28(3):390-402. doi: 10.1177/0394632015588439. Epub 2015 Jul 27. Int J Immunopathol Pharmacol. 2015. PMID: 26216908
Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies.
D'souza N, Rossignoli F, Golinelli G, Grisendi G, Spano C, Candini O, Osturu S, Catani F, Paolucci P, Horwitz EM, Dominici M. D'souza N, et al. BMC Med. 2015 Aug 12;13:186. doi: 10.1186/s12916-015-0426-0. BMC Med. 2015. PMID: 26265166 Free PMC article. Review.
Tumor Stroma Manipulation By MSC.
Grisendi G, Spano C, Rossignoli F, D Souza N, Golinelli G, Fiori A, Horwitz EM, Guarneri V, Piacentini F, Paolucci P, Dominici M. Grisendi G, et al. Curr Drug Targets. 2016;17(10):1111-26. doi: 10.2174/1389450117666160307143226. Curr Drug Targets. 2016. PMID: 26953248 Review.
Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis.
Candini O, Spano C, Murgia A, Grisendi G, Veronesi E, Piccinno MS, Ferracin M, Negrini M, Giacobbi F, Bambi F, Horwitz EM, Conte P, Paolucci P, Dominici M. Candini O, et al. Stem Cells. 2015 Mar;33(3):939-50. doi: 10.1002/stem.1897. Stem Cells. 2015. PMID: 25428821
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