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Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
Sweis RF, Pliushchev M, Brown PJ, Guo J, Li F, Maag D, Petros AM, Soni NB, Tse C, Vedadi M, Michaelides MR, Chiang GG, Pappano WN.
Sweis RF, et al. Among authors: pappano wn.
ACS Med Chem Lett. 2014 Jan 2;5(2):205-9. doi: 10.1021/ml400496h. eCollection 2014 Feb 13.
ACS Med Chem Lett. 2014.
PMID: 24900801
Free PMC article.
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Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.
Sweis RF, Wang Z, Algire M, Arrowsmith CH, Brown PJ, Chiang GG, Guo J, Jakob CG, Kennedy S, Li F, Maag D, Shaw B, Soni NB, Vedadi M, Pappano WN.
Sweis RF, et al. Among authors: pappano wn.
ACS Med Chem Lett. 2015 Apr 29;6(6):695-700. doi: 10.1021/acsmedchemlett.5b00124. eCollection 2015 Jun 11.
ACS Med Chem Lett. 2015.
PMID: 26101576
Free PMC article.
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Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605.
Pappano WN, Jung PM, Meulbroek JA, Wang YC, Hubbard RD, Zhang Q, Grudzien MM, Soni NB, Johnson EF, Sheppard GS, Donawho C, Buchanan FG, Davidsen SK, Bell RL, Wang J.
Pappano WN, et al.
BMC Cancer. 2009 Sep 4;9:314. doi: 10.1186/1471-2407-9-314.
BMC Cancer. 2009.
PMID: 19732452
Free PMC article.
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Sonic hedgehog function in chondrichthyan fins and the evolution of appendage patterning.
Dahn RD, Davis MC, Pappano WN, Shubin NH.
Dahn RD, et al. Among authors: pappano wn.
Nature. 2007 Jan 18;445(7125):311-4. doi: 10.1038/nature05436. Epub 2006 Dec 24.
Nature. 2007.
PMID: 17187056
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