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Phase separation in biology and disease-a symposium report.
Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL. Cable J, et al. Among authors: pappu rv. Ann N Y Acad Sci. 2019 Sep;1452(1):3-11. doi: 10.1111/nyas.14126. Epub 2019 Jun 14. Ann N Y Acad Sci. 2019. PMID: 31199001 Free PMC article.
Coexisting Liquid Phases Underlie Nucleolar Subcompartments.
Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP. Feric M, et al. Among authors: pappu rv. Cell. 2016 Jun 16;165(7):1686-1697. doi: 10.1016/j.cell.2016.04.047. Epub 2016 May 19. Cell. 2016. PMID: 27212236 Free PMC article.
Functional Implications of Intracellular Phase Transitions.
Holehouse AS, Pappu RV. Holehouse AS, et al. Among authors: pappu rv. Biochemistry. 2018 May 1;57(17):2415-2423. doi: 10.1021/acs.biochem.7b01136. Epub 2018 Jan 24. Biochemistry. 2018. PMID: 29323488 Free PMC article.
Phase Separation of Intrinsically Disordered Proteins.
Posey AE, Holehouse AS, Pappu RV. Posey AE, et al. Among authors: pappu rv. Methods Enzymol. 2018;611:1-30. doi: 10.1016/bs.mie.2018.09.035. Epub 2018 Oct 31. Methods Enzymol. 2018. PMID: 30471685
Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties.
Boeynaems S, Holehouse AS, Weinhardt V, Kovacs D, Van Lindt J, Larabell C, Van Den Bosch L, Das R, Tompa PS, Pappu RV, Gitler AD. Boeynaems S, et al. Among authors: pappu rv. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7889-7898. doi: 10.1073/pnas.1821038116. Epub 2019 Mar 29. Proc Natl Acad Sci U S A. 2019. PMID: 30926670 Free PMC article.
182 results