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Nf1 has an essential role in endothelial cells.
Gitler AD, Zhu Y, Ismat FA, Lu MM, Yamauchi Y, Parada LF, Epstein JA. Gitler AD, et al. Among authors: Parada LF. Nat Genet. 2003 Jan;33(1):75-9. doi: 10.1038/ng1059. Epub 2002 Dec 9. Nat Genet. 2003. PMID: 12469121 Free PMC article.
Mice lacking neurofibromin develop gastric hyperplasia.
Lin L, Chen J, Richardson JA, Parada LF. Lin L, et al. Among authors: Parada LF. Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G751-61. doi: 10.1152/ajpgi.00007.2009. Epub 2009 Aug 6. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19661150 Free PMC article.
Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.
Lubeck BA, Lapinski PE, Oliver JA, Ksionda O, Parada LF, Zhu Y, Maillard I, Chiang M, Roose J, King PD. Lubeck BA, et al. Among authors: Parada LF. J Immunol. 2015 Jul 1;195(1):31-5. doi: 10.4049/jimmunol.1402639. Epub 2015 May 22. J Immunol. 2015. PMID: 26002977 Free PMC article.
Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Kwon CH, et al. Among authors: Parada LF. Cancer Res. 2008 May 1;68(9):3286-94. doi: 10.1158/0008-5472.CAN-07-6867. Cancer Res. 2008. PMID: 18451155 Free PMC article.
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