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81 results
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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.
Paradis S, Ruvkun G. Paradis S, et al. Genes Dev. 1998 Aug 15;12(16):2488-98. doi: 10.1101/gad.12.16.2488. Genes Dev. 1998. PMID: 9716402 Free PMC article.
The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines.
Tolias KF, Bikoff JB, Burette A, Paradis S, Harrar D, Tavazoie S, Weinberg RJ, Greenberg ME. Tolias KF, et al. Among authors: paradis s. Neuron. 2005 Feb 17;45(4):525-38. doi: 10.1016/j.neuron.2005.01.024. Neuron. 2005. PMID: 15721239
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.
Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G. Paradis S, et al. Genes Dev. 1999 Jun 1;13(11):1438-52. doi: 10.1101/gad.13.11.1438. Genes Dev. 1999. PMID: 10364160 Free PMC article.
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.
Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G. Ogg S, et al. Among authors: paradis s. Nature. 1997 Oct 30;389(6654):994-9. doi: 10.1038/40194. Nature. 1997. PMID: 9353126
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.
Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME. Flavell SW, et al. Among authors: paradis s. Science. 2006 Feb 17;311(5763):1008-12. doi: 10.1126/science.1122511. Science. 2006. PMID: 16484497
An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development.
Paradis S, Harrar DB, Lin Y, Koon AC, Hauser JL, Griffith EC, Zhu L, Brass LF, Chen C, Greenberg ME. Paradis S, et al. Neuron. 2007 Jan 18;53(2):217-32. doi: 10.1016/j.neuron.2006.12.012. Neuron. 2007. PMID: 17224404 Free PMC article.
Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.
Ghiretti AE, Moore AR, Brenner RG, Chen LF, West AE, Lau NC, Van Hooser SD, Paradis S. Ghiretti AE, et al. Among authors: paradis s. J Neurosci. 2014 Jan 8;34(2):392-407. doi: 10.1523/JNEUROSCI.1328-13.2014. J Neurosci. 2014. PMID: 24403140 Free PMC article.
CaMKII-dependent phosphorylation of the GTPase Rem2 is required to restrict dendritic complexity.
Ghiretti AE, Kenny K, Marr MT 2nd, Paradis S. Ghiretti AE, et al. Among authors: paradis s. J Neurosci. 2013 Apr 10;33(15):6504-15. doi: 10.1523/JNEUROSCI.3861-12.2013. J Neurosci. 2013. PMID: 23575848 Free PMC article.
TDP-43 misexpression causes defects in dendritic growth.
Herzog JJ, Deshpande M, Shapiro L, Rodal AA, Paradis S. Herzog JJ, et al. Among authors: paradis s. Sci Rep. 2017 Nov 15;7(1):15656. doi: 10.1038/s41598-017-15914-4. Sci Rep. 2017. PMID: 29142232 Free PMC article.
A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.
Moore AR, Ghiretti AE, Paradis S. Moore AR, et al. Among authors: paradis s. PLoS One. 2013 Aug 26;8(8):e74751. doi: 10.1371/journal.pone.0074751. eCollection 2013. PLoS One. 2013. PMID: 23991227 Free PMC article.
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