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Year Number of Results
2003 1
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37 results

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Page 1
Activation of parkin by a molecular glue.
Sauvé V, Stefan E, Croteau N, Goiran T, Fakih R, Bansal N, Hadzipasic A, Fang J, Murugan P, Chen S, Fon EA, Hirst WD, Silvian LF, Trempe JF, Gehring K. Sauvé V, et al. Among authors: murugan p. Nat Commun. 2024 Sep 19;15(1):7707. doi: 10.1038/s41467-024-51889-3. Nat Commun. 2024. PMID: 39300082 Free PMC article.
Discovery of Potent and Selective Reversible Ubiquitin-Like Modifier Activating Enzyme 5 Inhibitors Targeting the UFMylation Pathway.
Mignone JJ, Jurica EA, Rajasekaran D, Robustelli J, McCarthy C, Quang PQ, Guo Q, Ball DJ, Donnell AF, Mahon BP, Mulligan D, Spronk SA, Srivastava S, Vik EC, Cavallaro CL, Chattergoon FJ, Ellsworth BA, Joshi S, Lees E, Lawrence RM, Li L, Mai S, Manik MK, Marsilio F, Mavrakis K, Murugan P, Newitt JA, Sheth P, Tredup J, Traeger SC, Weis DD, Yan C, Yanchunas J Jr, Zhang P, Wrobleski ST, Kalev P, Bronson JJ. Mignone JJ, et al. Among authors: murugan p. J Med Chem. 2025 Oct 9;68(19):20827-20845. doi: 10.1021/acs.jmedchem.5c02305. Epub 2025 Sep 25. J Med Chem. 2025. PMID: 40994290
Angiomotins link F-actin architecture to Hippo pathway signaling.
Mana-Capelli S, Paramasivam M, Dutta S, McCollum D. Mana-Capelli S, et al. Among authors: paramasivam m. Mol Biol Cell. 2014 May;25(10):1676-85. doi: 10.1091/mbc.E13-11-0701. Epub 2014 Mar 19. Mol Biol Cell. 2014. PMID: 24648494 Free PMC article.
ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis.
Ma B, Marcotte D, Paramasivam M, Michelsen K, Wang T, Bertolotti-Ciarlet A, Jones JH, Moree B, Butko M, Salafsky J, Sun X, McKee T, Silvian LF. Ma B, et al. Among authors: paramasivam m. PLoS One. 2016 Nov 10;11(11):e0165983. doi: 10.1371/journal.pone.0165983. eCollection 2016. PLoS One. 2016. PMID: 27832137 Free PMC article.
Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension.
Marcotte D, Rushe M, M Arduini R, Lukacs C, Atkins K, Sun X, Little K, Cullivan M, Paramasivam M, Patterson TA, Hesson T, D McKee T, May-Dracka TL, Xin Z, Bertolotti-Ciarlet A, Bhisetti GR, Lyssikatos JP, Silvian LF. Marcotte D, et al. Among authors: paramasivam m. Protein Sci. 2017 Feb;26(2):152-162. doi: 10.1002/pro.3062. Epub 2016 Oct 21. Protein Sci. 2017. PMID: 27727493 Free PMC article.
Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase.
Shlevkov E, Murugan P, Montagna D, Stefan E, Hadzipasic A, Harvey JS, Kumar PR, Entova S, Bansal N, Bickford S, Wong LY, Hirst WD, Weihofen A, Silvian LF. Shlevkov E, et al. Among authors: murugan p. iScience. 2021 Dec 18;25(1):103650. doi: 10.1016/j.isci.2021.103650. eCollection 2022 Jan 21. iScience. 2021. PMID: 35024585 Free PMC article.
37 results