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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.
Yu H, Kortylewski M, Pardoll D. Yu H, et al. Among authors: pardoll d. Nat Rev Immunol. 2007 Jan;7(1):41-51. doi: 10.1038/nri1995. Nat Rev Immunol. 2007. PMID: 17186030 Review.
GM-CSF gene-modifed cancer cell immunotherapies: of mice and men.
Hege KM, Jooss K, Pardoll D. Hege KM, et al. Among authors: pardoll d. Int Rev Immunol. 2006 Sep-Dec;25(5-6):321-52. doi: 10.1080/08830180600992498. Int Rev Immunol. 2006. PMID: 17169779 Review.
STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients.
Vasquez-Dunddel D, Pan F, Zeng Q, Gorbounov M, Albesiano E, Fu J, Blosser RL, Tam AJ, Bruno T, Zhang H, Pardoll D, Kim Y. Vasquez-Dunddel D, et al. Among authors: pardoll d. J Clin Invest. 2013 Apr;123(4):1580-9. doi: 10.1172/JCI60083. J Clin Invest. 2013. PMID: 23454751 Free PMC article.
A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors.
Lee H, Deng J, Xin H, Liu Y, Pardoll D, Yu H. Lee H, et al. Among authors: pardoll d. Cancer Res. 2011 Jun 1;71(11):3772-80. doi: 10.1158/0008-5472.CAN-10-3304. Epub 2011 Apr 18. Cancer Res. 2011. PMID: 21502401 Free PMC article.
STATs in cancer inflammation and immunity: a leading role for STAT3.
Yu H, Pardoll D, Jove R. Yu H, et al. Among authors: pardoll d. Nat Rev Cancer. 2009 Nov;9(11):798-809. doi: 10.1038/nrc2734. Nat Rev Cancer. 2009. PMID: 19851315 Free PMC article. Review.
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment.
Kortylewski M, Xin H, Kujawski M, Lee H, Liu Y, Harris T, Drake C, Pardoll D, Yu H. Kortylewski M, et al. Among authors: pardoll d. Cancer Cell. 2009 Feb 3;15(2):114-23. doi: 10.1016/j.ccr.2008.12.018. Cancer Cell. 2009. PMID: 19185846 Free PMC article.
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.
Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S, Niu G, Kay H, Mulé J, Kerr WG, Jove R, Pardoll D, Yu H. Kortylewski M, et al. Among authors: pardoll d. Nat Med. 2005 Dec;11(12):1314-21. doi: 10.1038/nm1325. Epub 2005 Nov 20. Nat Med. 2005. PMID: 16288283
Role of Stat3 in regulating p53 expression and function.
Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Niu G, et al. Among authors: pardoll d. Mol Cell Biol. 2005 Sep;25(17):7432-40. doi: 10.1128/MCB.25.17.7432-7440.2005. Mol Cell Biol. 2005. PMID: 16107692 Free PMC article.
Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects.
Burdelya L, Kujawski M, Niu G, Zhong B, Wang T, Zhang S, Kortylewski M, Shain K, Kay H, Djeu J, Dalton W, Pardoll D, Wei S, Yu H. Burdelya L, et al. Among authors: pardoll d. J Immunol. 2005 Apr 1;174(7):3925-31. doi: 10.4049/jimmunol.174.7.3925. J Immunol. 2005. PMID: 15778348 Free PMC article.
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: pardoll d. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372
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