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Microbiome influences on neuro-immune interactions in neurodegenerative disease.
Menees KB, Otero BA, Tansey MG. Menees KB, et al. Among authors: tansey mg. Int Rev Neurobiol. 2022;167:25-57. doi: 10.1016/bs.irn.2022.07.006. Epub 2022 Aug 27. Int Rev Neurobiol. 2022. PMID: 36427957 Review.
Mounting evidence points to a role for the gut microbiome in a wide range of central nervous system diseases and disorders including depression, multiple sclerosis, Alzheimer's disease, Parkinson's disease, and autism spectrum disorder. M …
Mounting evidence points to a role for the gut microbiome in a wide range of central nervous system diseases and disorders including …
Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms.
Xie A, Ensink E, Li P, Gordevičius J, Marshall LL, George S, Pospisilik JA, Aho VTE, Houser MC, Pereira PAB, Rudi K, Paulin L, Tansey MG, Auvinen P, Brundin P, Brundin L, Labrie V, Scheperjans F. Xie A, et al. Among authors: tansey mg. Mov Disord. 2022 Aug;37(8):1644-1653. doi: 10.1002/mds.29128. Epub 2022 Jun 20. Mov Disord. 2022. PMID: 35723531 Free PMC article.
BACKGROUND: The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease (PD) patients. ...Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder …
BACKGROUND: The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease …
Inflammation and immune dysfunction in Parkinson disease.
Tansey MG, Wallings RL, Houser MC, Herrick MK, Keating CE, Joers V. Tansey MG, et al. Nat Rev Immunol. 2022 Nov;22(11):657-673. doi: 10.1038/s41577-022-00684-6. Epub 2022 Mar 4. Nat Rev Immunol. 2022. PMID: 35246670 Free PMC article. Review.
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and involves a fundamental role of neuroinflammation in its pathophysiology. ...Moreover, numerous studies of peripheral blo …
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central …
Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson's disease.
Aho VTE, Houser MC, Pereira PAB, Chang J, Rudi K, Paulin L, Hertzberg V, Auvinen P, Tansey MG, Scheperjans F. Aho VTE, et al. Among authors: tansey mg. Mol Neurodegener. 2021 Feb 8;16(1):6. doi: 10.1186/s13024-021-00427-6. Mol Neurodegener. 2021. PMID: 33557896 Free PMC article.
BACKGROUND: Previous studies have reported that gut microbiota, permeability, short-chain fatty acids (SCFAs), and inflammation are altered in Parkinson's disease (PD), but how these factors are linked and how they contribute to disease processe …
BACKGROUND: Previous studies have reported that gut microbiota, permeability, short-chain fatty acids (SCFAs), and inflammation are a …
Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series.
Joers V, Masilamoni G, Kempf D, Weiss AR, Rotterman TM, Murray B, Yalcin-Cakmakli G, Voll RJ, Goodman MM, Howell L, Bachevalier J, Green SJ, Naqib A, Shaikh M, Engen PA, Keshavarzian A, Barnum CJ, Nye JA, Smith Y, Tansey MG. Joers V, et al. Among authors: tansey mg. Neurobiol Dis. 2020 Oct;144:105027. doi: 10.1016/j.nbd.2020.105027. Epub 2020 Jul 24. Neurobiol Dis. 2020. PMID: 32712266 Free PMC article.
Inflammation has been linked to the development of nonmotor symptoms in Parkinson's disease (PD), which greatly impact patients' quality of life and can often precede motor symptoms. ...Potential other sex differences were observed in circulating inflammation …
Inflammation has been linked to the development of nonmotor symptoms in Parkinson's disease (PD), which greatly impact …
The gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis?
Houser MC, Tansey MG. Houser MC, et al. Among authors: tansey mg. NPJ Parkinsons Dis. 2017 Jan 11;3:3. doi: 10.1038/s41531-016-0002-0. eCollection 2017. NPJ Parkinsons Dis. 2017. PMID: 28649603 Free PMC article.
We review the evidence that intestinal dysfunction is present in Parkinson's disease and that it may reflect the earliest manifestations of Parkinson's disease pathology, and we link these findings to dysregulated immune activity. Based o …
We review the evidence that intestinal dysfunction is present in Parkinson's disease and that it may reflect the earlie …