AS-IV attenuates nigral NLRP3 inflammasome in a Parkinson's disease mouse model via gut microbiota.
Cai J, Wang M, You Y, Sun F, Wang M, Wang N, Wang R, Zhang K, Ge R, Wang H.
Cai J, et al.
Commun Biol. 2026 Jun 6. doi: 10.1038/s42003-026-10415-5. Online ahead of print.
Commun Biol. 2026.
PMID: 42251131
Free article.
Astragaloside IV (AS-IV) neuroprotection against rotenone (ROT)-induced Parkinson's pathology was examined via microbiota-gut-brain axis mechanisms. Methods included intraperitoneal AS-IV, fecal microbiota transplantation (FMT) from AS-IV-treated mice, …
Astragaloside IV (AS-IV) neuroprotection against rotenone (ROT)-induced Parkinson's pathology was examined via microbiota …