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2,026 results

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Page 1
Parkinson's Disease and Parkinsonism.
Hayes MT. Hayes MT. Am J Med. 2019 Jul;132(7):802-807. doi: 10.1016/j.amjmed.2019.03.001. Epub 2019 Mar 16. Am J Med. 2019. PMID: 30890425 Review.
Parkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a common neurologic ailment. ...Unlike other neurodegenerative diseases, idiopathic Parkinson's disease has effective tr …
Parkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a …
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA, Noyce AJ, Xue A, Bras J, Young E, von Coelln R, Simón-Sánchez J, Schulte C, Sharma M, Krohn L, Pihlstrøm L, Siitonen A, Iwaki H, Leonard H, Faghri F, Gibbs JR, Hernandez DG, Scholz SW, Botia JA, Martinez M, Corvol JC, Lesage S, Jankovic J, Shulman LM, Sutherland M, Tienari P, Majamaa K, Toft M, Andreassen OA, Bangale T, Brice A, Yang J, Gan-Or Z, Gasser T, Heutink P, Shulman JM, Wood NW, Hinds DA, Hardy JA, Morris HR, Gratten J, Visscher PM, Graham RR, Singleton AB; 23andMe Research Team; System Genomics of Parkinson's Disease Consortium; International Parkinson's Disease Genomics Consortium. Nalls MA, et al. Lancet Neurol. 2019 Dec;18(12):1091-1102. doi: 10.1016/S1474-4422(19)30320-5. Lancet Neurol. 2019. PMID: 31701892 Free PMC article.
BACKGROUND: Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological knowledge about the disease over the past decade. We aimed to use the largest aggregate of GWAS data to identify novel risk loci and gain f …
BACKGROUND: Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological knowle …
Preventing Parkinson's Disease: An Environmental Agenda.
De Miranda BR, Goldman SM, Miller GW, Greenamyre JT, Dorsey ER. De Miranda BR, et al. J Parkinsons Dis. 2022;12(1):45-68. doi: 10.3233/JPD-212922. J Parkinsons Dis. 2022. PMID: 34719434 Free PMC article. Review.
Fueled by aging populations and continued environmental contamination, the global burden of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases, have multiple environmental and genetic influences but no approved disea …
Fueled by aging populations and continued environmental contamination, the global burden of Parkinson's disease (PD) is …
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease.
Nakajima A, Ohizumi Y. Nakajima A, et al. Int J Mol Sci. 2019 Jul 10;20(14):3380. doi: 10.3390/ijms20143380. Int J Mol Sci. 2019. PMID: 31295812 Free PMC article. Review.
Alzheimer's disease (AD), which is characterized by the presence of amyloid-beta (Abeta) plaques and neurofibrillary tangles, accompanied by neurodegeneration, is the most common form of age-related neurodegenerative disease. Parkinson's disease …
Alzheimer's disease (AD), which is characterized by the presence of amyloid-beta (Abeta) plaques and neurofibrillary tangles, accompa …
Trichloroethylene: An Invisible Cause of Parkinson's Disease?
Dorsey ER, Zafar M, Lettenberger SE, Pawlik ME, Kinel D, Frissen M, Schneider RB, Kieburtz K, Tanner CM, De Miranda BR, Goldman SM, Bloem BR. Dorsey ER, et al. J Parkinsons Dis. 2023;13(2):203-218. doi: 10.3233/JPD-225047. J Parkinsons Dis. 2023. PMID: 36938742 Free PMC article. Review.
The etiologies of Parkinson's disease (PD) remain unclear. Some, such as certain genetic mutations and head trauma, are widely known or easily identified. ...
The etiologies of Parkinson's disease (PD) remain unclear. Some, such as certain genetic mutations and head trauma, are …
Pathophysiology of bradykinesia in Parkinson's disease.
Berardelli A, Rothwell JC, Thompson PD, Hallett M. Berardelli A, et al. Brain. 2001 Nov;124(Pt 11):2131-46. doi: 10.1093/brain/124.11.2131. Brain. 2001. PMID: 11673316 Review.
Bradykinesia means slowness of movement and is one of the cardinal manifestations of Parkinson's disease. Weakness, tremor and rigidity may contribute to but do not fully explain bradykinesia. ...For example, patients' problems in performing more than one tas …
Bradykinesia means slowness of movement and is one of the cardinal manifestations of Parkinson's disease. Weakness, tre …
Caregiver burden in Parkinson's disease: a mixed-methods study.
Geerlings AD, Kapelle WM, Sederel CJ, Tenison E, Wijngaards-Berenbroek H, Meinders MJ, Munneke M, Ben-Shlomo Y, Bloem BR, Darweesh SKL. Geerlings AD, et al. BMC Med. 2023 Jul 10;21(1):247. doi: 10.1186/s12916-023-02933-4. BMC Med. 2023. PMID: 37424022 Free PMC article.
BACKGROUND: Providing informal care for a person with Parkinson's disease (PD) can be a demanding process affecting several dimensions of a caregiver's life and potentially causing caregiver burden. ...The quantitative study included a standardized questionna …
BACKGROUND: Providing informal care for a person with Parkinson's disease (PD) can be a demanding process affecting sev …
Projections for prevalence of Parkinson's disease and its driving factors in 195 countries and territories to 2050: modelling study of Global Burden of Disease Study 2021.
Su D, Cui Y, He C, Yin P, Bai R, Zhu J, Lam JST, Zhang J, Yan R, Zheng X, Wu J, Zhao D, Wang A, Zhou M, Feng T. Su D, et al. BMJ. 2025 Mar 5;388:e080952. doi: 10.1136/bmj-2024-080952. BMJ. 2025. PMID: 40044233 Free PMC article.
OBJECTIVE: To predict the global, regional, and national prevalence of Parkinson's disease by age, sex, year, and Socio-demographic Index to 2050 and quantify the factors driving changes in Parkinson's disease cases. ...CONCLUSIONS: By 20 …
OBJECTIVE: To predict the global, regional, and national prevalence of Parkinson's disease by age, sex, year, and Socio …
Herbal Resources to Combat a Progressive & Degenerative Nervous System Disorder- Parkinson's Disease.
Singla RK, Agarwal T, He X, Shen B. Singla RK, et al. Curr Drug Targets. 2021;22(6):609-630. doi: 10.2174/1389450121999201013155202. Curr Drug Targets. 2021. PMID: 33050857 Review.
Parkinson's disease is one of the most common adult-onset, a chronic disorder involving neurodegeneration, which progressively leads to deprivation of dopaminergic neurons in substantia nigra, causing a subsequent reduction of dopamine levels in the striatum …
Parkinson's disease is one of the most common adult-onset, a chronic disorder involving neurodegeneration, which progre …
Employment Resources for People with Parkinson's Disease: A Resource Review and Needs Assessment.
Rafferty M, Stoff L, Palmentera P, Capraro P, Stanley I, Heinemann AW, Johnson K. Rafferty M, et al. J Occup Rehabil. 2021 Jun;31(2):275-284. doi: 10.1007/s10926-020-09915-w. J Occup Rehabil. 2021. PMID: 33025272
Purpose People with Parkinson's disease (PwP) exit the workforce on average 5 years earlier than people without Parkinson's due to motor, cognitive, communicative, and affective symptoms. ...Results Literature review and online searches yielded …
Purpose People with Parkinson's disease (PwP) exit the workforce on average 5 years earlier than people without Park …
2,026 results