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The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM. Parkinson A, et al. Toxicol Appl Pharmacol. 2004 Sep 15;199(3):193-209. doi: 10.1016/j.taap.2004.01.010. Toxicol Appl Pharmacol. 2004. PMID: 15364537 Review.
Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice.
Forkert PG, Lord JA, Parkinson A. Forkert PG, et al. Among authors: parkinson a. Carcinogenesis. 1996 Jan;17(1):127-32. doi: 10.1093/carcin/17.1.127. Carcinogenesis. 1996. PMID: 8565121
In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil.
Robertson P, DeCory HH, Madan A, Parkinson A. Robertson P, et al. Among authors: parkinson a. Drug Metab Dispos. 2000 Jun;28(6):664-71. Drug Metab Dispos. 2000. PMID: 10820139
Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.
Granvil CP, Madan A, Sharkawi M, Parkinson A, Wainer IW. Granvil CP, et al. Among authors: parkinson a. Drug Metab Dispos. 1999 Apr;27(4):533-41. Drug Metab Dispos. 1999. PMID: 10101149
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
Bullock P, Pearce R, Draper A, Podval J, Bracken W, Veltman J, Thomas P, Parkinson A. Bullock P, et al. Among authors: parkinson a. Drug Metab Dispos. 1995 Jul;23(7):736-48. Drug Metab Dispos. 1995. PMID: 7587963
Influence of extracellular matrix overlay and medium formulation on the induction of cytochrome P-450 2B enzymes in primary cultures of rat hepatocytes.
LeCluyse E, Bullock P, Madan A, Carroll K, Parkinson A. LeCluyse E, et al. Among authors: parkinson a. Drug Metab Dispos. 1999 Aug;27(8):909-15. Drug Metab Dispos. 1999. PMID: 10421618
Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes.
Madan A, DeHaan R, Mudra D, Carroll K, LeCluyse E, Parkinson A. Madan A, et al. Among authors: parkinson a. Drug Metab Dispos. 1999 Mar;27(3):327-35. Drug Metab Dispos. 1999. PMID: 10064562
An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials.
Parkinson A. Parkinson A. Toxicol Pathol. 1996 Jan-Feb;24(1):48-57. Toxicol Pathol. 1996. PMID: 8839280 Review.
Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.
Pearce RE, McIntyre CJ, Madan A, Sanzgiri U, Draper AJ, Bullock PL, Cook DC, Burton LA, Latham J, Nevins C, Parkinson A. Pearce RE, et al. Among authors: parkinson a. Arch Biochem Biophys. 1996 Jul 15;331(2):145-69. doi: 10.1006/abbi.1996.0294. Arch Biochem Biophys. 1996. PMID: 8660694
Identification of the human P450 enzymes involved in lansoprazole metabolism.
Pearce RE, Rodrigues AD, Goldstein JA, Parkinson A. Pearce RE, et al. Among authors: parkinson a. J Pharmacol Exp Ther. 1996 May;277(2):805-16. J Pharmacol Exp Ther. 1996. PMID: 8627562
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