Parkkari T - Search Results

1

Impaired Performance of the Q175 Mouse Model of Huntington's Disease in the Touch Screen Paired Associates Learning Task.

Piiponniemi TO, Parkkari T, Heikkinen T, Puoliväli J, Park LC, Cachope R, Kopanitsa MV. Piiponniemi TO, et al. Among authors: parkkari t. Front Behav Neurosci. 2018 Oct 2;12:226. doi: 10.3389/fnbeh.2018.00226. eCollection 2018. Front Behav Neurosci. 2018. PMID: 30333735 Free PMC article.

2

Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington's disease.

Heikkinen T, Bragge T, Bhattarai N, Parkkari T, Puoliväli J, Kontkanen O, Sweeney P, Park LC, Munoz-Sanjuan I. Heikkinen T, et al. Among authors: parkkari t. PLoS One. 2020 Dec 28;15(12):e0243052. doi: 10.1371/journal.pone.0243052. eCollection 2020. PLoS One. 2020. PMID: 33370315 Free PMC article.

3

Global Rhes knockout in the Q175 Huntington's disease mouse model.

Heikkinen T, Bragge T, Kuosmanen J, Parkkari T, Gustafsson S, Kwan M, Beltran J, Ghavami A, Subramaniam S, Shahani N, Ramírez-Jarquín UN, Park L, Muñoz-Sanjuán I, Marchionini DM. Heikkinen T, et al. Among authors: parkkari t. PLoS One. 2021 Oct 14;16(10):e0258486. doi: 10.1371/journal.pone.0258486. eCollection 2021. PLoS One. 2021. PMID: 34648564 Free PMC article.

4

Improved synthesis of [¹⁸F] fallypride and characterization of a Huntington's disease mouse model, zQ175DN KI, using longitudinal PET imaging of D2/D3 receptors.

Huhtala T, Poutiainen P, Rytkönen J, Lehtimäki K, Parkkari T, Kasanen I, Airaksinen AJ, Koivula T, Sweeney P, Kontkanen O, Wityak J, Dominiquez C, Park LC. Huhtala T, et al. Among authors: parkkari t. EJNMMI Radiopharm Chem. 2019 Aug 5;4(1):20. doi: 10.1186/s41181-019-0071-6. EJNMMI Radiopharm Chem. 2019. PMID: 31659519 Free PMC article.

5

Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists.

Yrjölä S, Sarparanta M, Airaksinen AJ, Hytti M, Kauppinen A, Pasonen-Seppänen S, Adinolfi B, Nieri P, Manera C, Keinänen O, Poso A, Nevalainen TJ, Parkkari T. Yrjölä S, et al. Among authors: parkkari t. Eur J Pharm Sci. 2015 Jan 25;67:85-96. doi: 10.1016/j.ejps.2014.11.003. Epub 2014 Nov 14. Eur J Pharm Sci. 2015. PMID: 25447744

6

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12).

Parkkari T, Haavikko R, Laitinen T, Navia-Paldanius D, Rytilahti R, Vaara M, Lehtonen M, Alakurtti S, Yli-Kauhaluoma J, Nevalainen T, Savinainen JR, Laitinen JT. Parkkari T, et al. PLoS One. 2014 May 30;9(5):e98286. doi: 10.1371/journal.pone.0098286. eCollection 2014. PLoS One. 2014. PMID: 24879289 Free PMC article.

7

Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A).

Savinainen JR, Patel JZ, Parkkari T, Navia-Paldanius D, Marjamaa JJ, Laitinen T, Nevalainen T, Laitinen JT. Savinainen JR, et al. Among authors: parkkari t. PLoS One. 2014 Oct 7;9(10):e109869. doi: 10.1371/journal.pone.0109869. eCollection 2014. PLoS One. 2014. PMID: 25290914 Free PMC article.

8

Discovery of novel cannabinoid receptor ligands by a virtual screening approach: further development of 2,4,6-trisubstituted 1,3,5-triazines as CB2 agonists.

Yrjölä S, Kalliokoski T, Laitinen T, Poso A, Parkkari T, Nevalainen T. Yrjölä S, et al. Among authors: parkkari t. Eur J Pharm Sci. 2013 Jan 23;48(1-2):9-20. doi: 10.1016/j.ejps.2012.10.020. Epub 2012 Nov 3. Eur J Pharm Sci. 2013. PMID: 23131798

9

1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling.

Käsnänen H, Minkkilä A, Taupila S, Patel JZ, Parkkari T, Lahtela-Kakkonen M, Saario SM, Nevalainen T, Poso A. Käsnänen H, et al. Among authors: parkkari t. Eur J Pharm Sci. 2013 Jun 14;49(3):423-33. doi: 10.1016/j.ejps.2013.03.015. Epub 2013 Apr 2. Eur J Pharm Sci. 2013. PMID: 23557840

10

CB₂ receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells.

Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A. Hytti M, et al. Among authors: parkkari t. Sci Rep. 2017 Nov 23;7(1):16169. doi: 10.1038/s41598-017-16524-w. Sci Rep. 2017. PMID: 29170454 Free PMC article.

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