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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.
A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, Deniz J, Ramirez C, Díaz M, Gallardo G, de Galarreta CR, Salazar J, Lopez F, Edwards P, Parks J, Andujar M, Tontonoz P, Castrillo A. A-Gonzalez N, et al. Among authors: Parks J. Immunity. 2009 Aug 21;31(2):245-58. doi: 10.1016/j.immuni.2009.06.018. Epub 2009 Jul 30. Immunity. 2009. PMID: 19646905 Free PMC article.
LXR signaling couples sterol metabolism to proliferation in the acquired immune response.
Bensinger SJ, Bradley MN, Joseph SB, Zelcer N, Janssen EM, Hausner MA, Shih R, Parks JS, Edwards PA, Jamieson BD, Tontonoz P. Bensinger SJ, et al. Among authors: Parks JS. Cell. 2008 Jul 11;134(1):97-111. doi: 10.1016/j.cell.2008.04.052. Cell. 2008. PMID: 18614014 Free PMC article.
Hepatic ABCA1 and VLDL triglyceride production.
Liu M, Chung S, Shelness GS, Parks JS. Liu M, et al. Among authors: Parks JS. Biochim Biophys Acta. 2012 May;1821(5):770-7. doi: 10.1016/j.bbalip.2011.09.020. Epub 2011 Oct 6. Biochim Biophys Acta. 2012. PMID: 22001232 Free PMC article. Review.
Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Mulya A, Lee JY, Gebre AK, Boudyguina EY, Chung SK, Smith TL, Colvin PL, Jiang XC, Parks JS. Mulya A, et al. Among authors: Parks JS. J Lipid Res. 2008 Nov;49(11):2390-401. doi: 10.1194/jlr.M800241-JLR200. Epub 2008 Jun 25. J Lipid Res. 2008. PMID: 18583707 Free PMC article.
ATP-binding cassette transporter AI and its role in HDL formation.
Lee JY, Parks JS. Lee JY, et al. Among authors: Parks JS. Curr Opin Lipidol. 2005 Feb;16(1):19-25. doi: 10.1097/00041433-200502000-00005. Curr Opin Lipidol. 2005. PMID: 15650559 Review.
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