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Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice.
Strowski MZ, Parmar RM, Blake AD, Schaeffer JM. Strowski MZ, et al. Among authors: parmar rm. Endocrinology. 2000 Jan;141(1):111-7. doi: 10.1210/endo.141.1.7263. Endocrinology. 2000. PMID: 10614629
Somatostatin receptor subtypes 2 and 5 inhibit corticotropin-releasing hormone-stimulated adrenocorticotropin secretion from AtT-20 cells.
Strowski MZ, Dashkevicz MP, Parmar RM, Wilkinson H, Kohler M, Schaeffer JM, Blake AD. Strowski MZ, et al. Among authors: parmar rm. Neuroendocrinology. 2002 Jun;75(6):339-46. doi: 10.1159/000059430. Neuroendocrinology. 2002. PMID: 12065886
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.
Ye Z, Gao Y, Bakshi RK, Chen MH, Rohrer SP, Feighner SD, Pong SS, Howard AD, Blake A, Birzin ET, Locco L, Parmar RM, Chan WW, Schaeffer JM, Smith RG, Patchett AA, Nargund RP. Ye Z, et al. Among authors: parmar rm. Bioorg Med Chem Lett. 2000 Jan 3;10(1):5-8. doi: 10.1016/s0960-894x(99)00584-3. Bioorg Med Chem Lett. 2000. PMID: 10636230
Nonpeptidyl somatostatin agonists demonstrate that sst2 and sst5 inhibit stimulated growth hormone secretion from rat anterior pituitary cells.
Parmar RM, Chan WW, Dashkevicz M, Hayes EC, Rohrer SP, Smith RG, Schaeffer JM, Blake AD. Parmar RM, et al. Biochem Biophys Res Commun. 1999 Sep 24;263(2):276-80. doi: 10.1006/bbrc.1999.1376. Biochem Biophys Res Commun. 1999. PMID: 10491284
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.
Yang L, Berk SC, Rohrer SP, Mosley RT, Guo L, Underwood DJ, Arison BH, Birzin ET, Hayes EC, Mitra SW, Parmar RM, Cheng K, Wu TJ, Butler BS, Foor F, Pasternak A, Pan Y, Silva M, Freidinger RM, Smith RG, Chapman K, Schaeffer JM, Patchett AA. Yang L, et al. Among authors: parmar rm. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. doi: 10.1073/pnas.95.18.10836. Proc Natl Acad Sci U S A. 1998. PMID: 9724791 Free PMC article.
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.
Rohrer SP, Birzin ET, Mosley RT, Berk SC, Hutchins SM, Shen DM, Xiong Y, Hayes EC, Parmar RM, Foor F, Mitra SW, Degrado SJ, Shu M, Klopp JM, Cai SJ, Blake A, Chan WW, Pasternak A, Yang L, Patchett AA, Smith RG, Chapman KT, Schaeffer JM. Rohrer SP, et al. Among authors: parmar rm. Science. 1998 Oct 23;282(5389):737-40. doi: 10.1126/science.282.5389.737. Science. 1998. PMID: 9784130 Free article.
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