Parrington J - Search Results

1

Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.

Ruas M, Davis LC, Chen CC, Morgan AJ, Chuang KT, Walseth TF, Grimm C, Garnham C, Powell T, Platt N, Platt FM, Biel M, Wahl-Schott C, Parrington J, Galione A. Ruas M, et al. Among authors: parrington j. EMBO J. 2015 Jul 2;34(13):1743-58. doi: 10.15252/embj.201490009. Epub 2015 Apr 14. EMBO J. 2015. PMID: 25872774 Free PMC article.

2

Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.

Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A. Ruas M, et al. Among authors: parrington j. Curr Biol. 2010 Apr 27;20(8):703-9. doi: 10.1016/j.cub.2010.02.049. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346675 Free PMC article.

3

NAADP as an intracellular messenger regulating lysosomal calcium-release channels.

Galione A, Morgan AJ, Arredouani A, Davis LC, Rietdorf K, Ruas M, Parrington J. Galione A, et al. Among authors: parrington j. Biochem Soc Trans. 2010 Dec;38(6):1424-31. doi: 10.1042/BST0381424. Biochem Soc Trans. 2010. PMID: 21118101

4

Physiological roles of NAADP-mediated Ca2+ signaling.

Galione A, Parrington J, Funnell T. Galione A, et al. Among authors: parrington j. Sci China Life Sci. 2011 Aug;54(8):725-32. doi: 10.1007/s11427-011-4207-5. Epub 2011 Jul 24. Sci China Life Sci. 2011. PMID: 21786195 Free article. Review.

5

Two-pore channels form homo- and heterodimers.

Rietdorf K, Funnell TM, Ruas M, Heinemann J, Parrington J, Galione A. Rietdorf K, et al. Among authors: parrington j. J Biol Chem. 2011 Oct 28;286(43):37058-62. doi: 10.1074/jbc.C111.289835. Epub 2011 Sep 8. J Biol Chem. 2011. PMID: 21903581 Free PMC article.

6

The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.

Morgan AJ, Parrington J, Galione A. Morgan AJ, et al. Among authors: parrington j. Cell Calcium. 2012 Dec;52(6):481-7. doi: 10.1016/j.ceca.2012.09.001. Epub 2012 Oct 23. Cell Calcium. 2012. PMID: 23099186 Free PMC article.

7

Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles.

Morgan AJ, Davis LC, Wagner SK, Lewis AM, Parrington J, Churchill GC, Galione A. Morgan AJ, et al. Among authors: parrington j. J Cell Biol. 2013 Mar 18;200(6):789-805. doi: 10.1083/jcb.201204078. Epub 2013 Mar 11. J Cell Biol. 2013. PMID: 23479744 Free PMC article.

8

TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2.

Ruas M, Chuang KT, Davis LC, Al-Douri A, Tynan PW, Tunn R, Teboul L, Galione A, Parrington J. Ruas M, et al. Among authors: parrington j. Mol Cell Biol. 2014 Nov;34(21):3981-92. doi: 10.1128/MCB.00113-14. Epub 2014 Aug 18. Mol Cell Biol. 2014. PMID: 25135478 Free PMC article.

9

Preparation and use of sea urchin egg homogenates for studying NAADP-mediated Ca²⁺ release.

Galione A, Chuang KT, Funnell TM, Davis LC, Morgan AJ, Ruas M, Parrington J, Churchill GC. Galione A, et al. Among authors: parrington j. Cold Spring Harb Protoc. 2014 Sep 2;2014(9):988-92. doi: 10.1101/pdb.prot076901. Cold Spring Harb Protoc. 2014. PMID: 25183812

10

Synthesis of [³²P]NAADP for the radioreceptor binding assay.

Galione A, Chuang KT, Funnell TM, Davis LC, Morgan AJ, Ruas M, Parrington J, Churchill GC. Galione A, et al. Among authors: parrington j. Cold Spring Harb Protoc. 2014 Sep 2;2014(9):993-5. doi: 10.1101/pdb.prot076919. Cold Spring Harb Protoc. 2014. PMID: 25183813

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