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ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis.
Fagan AM, Christopher E, Taylor JW, Parsadanian M, Spinner M, Watson M, Fryer JD, Wahrle S, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Among authors: parsadanian m. Am J Pathol. 2004 Oct;165(4):1413-22. doi: 10.1016/s0002-9440(10)63399-8. Am J Pathol. 2004. PMID: 15466405 Free PMC article.
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: parsadanian m. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.
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