Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds.
Alves VM, Muratov E, Fourches D, Strickland J, Kleinstreuer N, Andrade CH, Tropsha A.
Alves VM, et al.
Toxicol Appl Pharmacol. 2015 Apr 15;284(2):262-72. doi: 10.1016/j.taap.2014.12.014. Epub 2015 Jan 3.
Toxicol Appl Pharmacol. 2015.
PMID: 25560674
Free PMC article.
Repetitive exposure to a chemical agent can induce an immune reaction in inherently susceptible individuals that leads to skin sensitization. Although many chemicals have been reported as skin sensitizers, there have been very few rigorously validated …
Repetitive exposure to a chemical agent can induce an immune reaction in inherently susceptible individuals that leads to skin sen …