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Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis.
Iversen K, Ihlemann N, Gill SU, Madsen T, Elming H, Jensen KT, Bruun NE, Høfsten DE, Fursted K, Christensen JJ, Schultz M, Klein CF, Fosbøll EL, Rosenvinge F, Schønheyder HC, Køber L, Torp-Pedersen C, Helweg-Larsen J, Tønder N, Moser C, Bundgaard H. Iversen K, et al. N Engl J Med. 2019 Jan 31;380(5):415-424. doi: 10.1056/NEJMoa1808312. Epub 2018 Aug 28. N Engl J Med. 2019. PMID: 30152252 Clinical Trial.
BACKGROUND: Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antibiotic agents for up to 6 weeks. ...CONCLUSIONS: In patients with endocarditis on the left side of the heart who were in st …
BACKGROUND: Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antib
A comparison of different antibiotic regimens for the treatment of infective endocarditis.
Martí-Carvajal AJ, Dayer M, Conterno LO, Gonzalez Garay AG, Martí-Amarista CE. Martí-Carvajal AJ, et al. Cochrane Database Syst Rev. 2020 May 14;5(5):CD009880. doi: 10.1002/14651858.CD009880.pub3. Cochrane Database Syst Rev. 2020. PMID: 32407558 Free PMC article.
One trial compared fosfomycin plus imipenem 3/4 (75%) versus vancomycin 0/4 (0%) (RR 7.00, 95% CI 0.47 to 103.27), and one trial compared partial oral treatment 7/201 (3.5%) versus conventional intravenous treatment 13/199 (6.53%) …
One trial compared fosfomycin plus imipenem 3/4 (75%) versus vancomycin 0/4 (0%) (RR 7.00, 95% CI 0.47 to 103.27), and one trial comp …
Partial oral versus full intravenous antibiotic treatment of endocarditis in people who inject drugs: A systematic review.
Brown A, Jefferson HL, Daley P, Kent WD, Webster D, Adams C. Brown A, et al. J Assoc Med Microbiol Infect Dis Can. 2024 Jan 16;8(4):253-261. doi: 10.3138/jammi-2023-0013. eCollection 2024 Jan. J Assoc Med Microbiol Infect Dis Can. 2024. PMID: 38250624 Free PMC article.
BACKGROUND: Prolonged intravenous (IV) antibiotic therapy may not be optimal for people who inject drugs (PWID) with infective endocarditis (IE) due to unique social and medical needs. The role of partial IV antibiotic therapy with …
BACKGROUND: Prolonged intravenous (IV) antibiotic therapy may not be optimal for people who inject drugs (PWID) with in …
The impact of partial-oral endocarditis treatment on anxiety and depression in the POET trial.
Bundgaard JS, Iversen K, Pries-Heje M, Ihlemann N, Bak TS, Østergaard L, Gill SU, Madsen T, Elming H, Jensen KT, Bruun NE, Høfsten DE, Fuursted K, Christensen JJ, Schultz M, Rosenvinge F, Schønheyder HC, Helweg-Larsen J, Køber L, Torp-Pedersen C, Fosbøl EL, Tønder N, Moser C, Bundgaard H, Mogensen UM. Bundgaard JS, et al. J Psychosom Res. 2022 Mar;154:110718. doi: 10.1016/j.jpsychores.2022.110718. Epub 2022 Jan 13. J Psychosom Res. 2022. PMID: 35078079 Clinical Trial.
BACKGROUND: The Partial-Oral versus Intravenous Antibiotic Treatment of Endocarditis Trial (POET) found that partial-oral outpatient treatment was non-inferior to conventional in-hospital intravenous
BACKGROUND: The Partial-Oral versus Intravenous Antibiotic Treatment of Endocarditis Trial …
Partial oral antibiotic therapy is non-inferior to intravenous therapy in non-critically ill patients with infective endocarditis : Review and meta-analysis.
Rezar R, Jirak P, Lichtenauer M, Jung C, Lauten A, Hoppe UC, Wernly B. Rezar R, et al. Wien Klin Wochenschr. 2020 Dec;132(23-24):762-769. doi: 10.1007/s00508-020-01614-z. Epub 2020 Feb 10. Wien Klin Wochenschr. 2020. PMID: 32040621 Free PMC article. Review.
BACKGROUND: Antimicrobial therapy is a cornerstone in the treatment of infective endocarditis (IE). ...Several trials evaluating the efficacy of partial oral therapy (POT) have been published. This article aimed to review and meta-analyze …
BACKGROUND: Antimicrobial therapy is a cornerstone in the treatment of infective endocarditis (IE). ...Several trials e …
Severity of anaemia and association with all-cause mortality in patients with medically managed left-sided endocarditis.
Pries-Heje MM, Hasselbalch RB, Wiingaard C, Fosbøl EL, Glenthøj AB, Ihlemann N, Gill SUA, Christiansen U, Elming H, Bruun NE, Povlsen JA, Helweg-Larsen J, Schultz M, Østergaard L, Fursted K, Christensen JJ, Rosenvinge F, Køber L, Tønder N, Moser C, Iversen K, Bundgaard H. Pries-Heje MM, et al. Heart. 2022 May 12;108(11):882-888. doi: 10.1136/heartjnl-2021-319637. Heart. 2022. PMID: 34611042 Clinical Trial.
OBJECTIVE: To assess the prevalence and severity of anaemia in patients with left-sided infective endocarditis (IE) and association with mortality. METHODS: In the Partial Oral versus Intravenous Antibiotic Treatment of Endocard
OBJECTIVE: To assess the prevalence and severity of anaemia in patients with left-sided infective endocarditis (IE) and association w …