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412 results
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Integrin regulation.
Ginsberg MH, Partridge A, Shattil SJ. Ginsberg MH, et al. Among authors: partridge a. Curr Opin Cell Biol. 2005 Oct;17(5):509-16. doi: 10.1016/j.ceb.2005.08.010. Curr Opin Cell Biol. 2005. PMID: 16099636 Review.
The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.
Petrich BG, Fogelstrand P, Partridge AW, Yousefi N, Ablooglu AJ, Shattil SJ, Ginsberg MH. Petrich BG, et al. J Clin Invest. 2007 Aug;117(8):2250-9. doi: 10.1172/JCI31024. J Clin Invest. 2007. PMID: 17627302 Free PMC article.
Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state.
Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. Partridge AW, et al. J Biol Chem. 2005 Feb 25;280(8):7294-300. doi: 10.1074/jbc.M412701200. Epub 2004 Dec 10. J Biol Chem. 2005. PMID: 15591321
Structural basis of integrin activation by talin.
Wegener KL, Partridge AW, Han J, Pickford AR, Liddington RC, Ginsberg MH, Campbell ID. Wegener KL, et al. Cell. 2007 Jan 12;128(1):171-82. doi: 10.1016/j.cell.2006.10.048. Cell. 2007. PMID: 17218263
Integrin activation by talin.
Ratnikov BI, Partridge AW, Ginsberg MH. Ratnikov BI, et al. Among authors: partridge aw. J Thromb Haemost. 2005 Aug;3(8):1783-90. doi: 10.1111/j.1538-7836.2005.01362.x. J Thromb Haemost. 2005. PMID: 16102045 Review.
Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles.
Lau TL, Partridge AW, Ginsberg MH, Ulmer TS. Lau TL, et al. Biochemistry. 2008 Apr 1;47(13):4008-16. doi: 10.1021/bi800107a. Epub 2008 Mar 6. Biochemistry. 2008. PMID: 18321071
Polar residue tagging of transmembrane peptides.
Melnyk RA, Partridge AW, Yip J, Wu Y, Goto NK, Deber CM. Melnyk RA, et al. Among authors: partridge aw. Biopolymers. 2003;71(6):675-85. doi: 10.1002/bip.10595. Biopolymers. 2003. PMID: 14991677
Transmembrane segment peptides with double D-amino acid replacements: helicity, hydrophobicity, and antimicrobial activity.
Maeda M, Melnyk RA, Partridge AW, Liu LP, Deber CM. Maeda M, et al. Among authors: partridge aw. Biopolymers. 2003;71(1):77-84. doi: 10.1002/bip.10383. Biopolymers. 2003. PMID: 12712502
A transmembrane segment mimic derived from Escherichia coli diacylglycerol kinase inhibits protein activity.
Partridge AW, Melnyk RA, Yang D, Bowie JU, Deber CM. Partridge AW, et al. J Biol Chem. 2003 Jun 13;278(24):22056-60. doi: 10.1074/jbc.M210685200. Epub 2003 Apr 9. J Biol Chem. 2003. PMID: 12686537
Polar mutations in membrane proteins as a biophysical basis for disease.
Partridge AW, Therien AG, Deber CM. Partridge AW, et al. Biopolymers. 2002;66(5):350-8. doi: 10.1002/bip.10313. Biopolymers. 2002. PMID: 12539263
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