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The mdx mouse model as a surrogate for Duchenne muscular dystrophy.
Partridge TA. Partridge TA. FEBS J. 2013 Sep;280(17):4177-86. doi: 10.1111/febs.12267. Epub 2013 Apr 22. FEBS J. 2013. PMID: 23551987 Free PMC article. Review.
Optimizing exon skipping therapies for DMD.
Yokota T, Duddy W, Partridge T. Yokota T, et al. Acta Myol. 2007 Dec;26(3):179-84. Acta Myol. 2007. PMID: 18646569 Free PMC article. Review.
"Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic.
Gordish-Dressman H, Willmann R, Dalle Pazze L, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbreun AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Patrick Gonzalez J, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A. Gordish-Dressman H, et al. J Neuromuscul Dis. 2018;5(4):407-417. doi: 10.3233/JND-180324. J Neuromuscul Dis. 2018. PMID: 30198876 Free PMC article.
Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients.
Hathout Y, Marathi RL, Rayavarapu S, Zhang A, Brown KJ, Seol H, Gordish-Dressman H, Cirak S, Bello L, Nagaraju K, Partridge T, Hoffman EP, Takeda S, Mah JK, Henricson E, McDonald C. Hathout Y, et al. Hum Mol Genet. 2014 Dec 15;23(24):6458-69. doi: 10.1093/hmg/ddu366. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027324 Free PMC article.
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy.
Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KRQ, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, Partridge T, Takeda S, Yokota T. Echigoya Y, et al. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4213-4218. doi: 10.1073/pnas.1613203114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373570 Free PMC article.
Dystrophin deficiency leads to disturbance of LAMP1-vesicle-associated protein secretion.
Duguez S, Duddy W, Johnston H, Lainé J, Le Bihan MC, Brown KJ, Bigot A, Hathout Y, Butler-Browne G, Partridge T. Duguez S, et al. Cell Mol Life Sci. 2013 Jun;70(12):2159-74. doi: 10.1007/s00018-012-1248-2. Epub 2013 Jan 24. Cell Mol Life Sci. 2013. PMID: 23344255
Could exon skipping help dystrophic boys to run, hop, and jump?
Partridge T. Partridge T. Mol Ther. 2014 Nov;22(11):1884-6. doi: 10.1038/mt.2014.189. Mol Ther. 2014. PMID: 25365985 Free PMC article. No abstract available.
Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia.
Duddy W, Duguez S, Johnston H, Cohen TV, Phadke A, Gordish-Dressman H, Nagaraju K, Gnocchi V, Low S, Partridge T. Duddy W, et al. Skelet Muscle. 2015 May 1;5:16. doi: 10.1186/s13395-015-0041-y. eCollection 2015. Skelet Muscle. 2015. PMID: 25987977 Free PMC article.
Greater Colo-Rectal Activation Phenotype in Exercised mdx Mice.
Nearing M, Novak J, Partridge T. Nearing M, et al. PLoS Curr. 2018 May 2;10:ecurrents.md.230ed3d6559b171e10279fc16e9ebef3. doi: 10.1371/currents.md.230ed3d6559b171e10279fc16e9ebef3. PLoS Curr. 2018. PMID: 29862132 Free PMC article.
Efficacy of Multi-exon Skipping Treatment in Duchenne Muscular Dystrophy Dog Model Neonates.
Lim KRQ, Echigoya Y, Nagata T, Kuraoka M, Kobayashi M, Aoki Y, Partridge T, Maruyama R, Takeda S, Yokota T. Lim KRQ, et al. Mol Ther. 2019 Jan 2;27(1):76-86. doi: 10.1016/j.ymthe.2018.10.011. Epub 2018 Oct 19. Mol Ther. 2019. PMID: 30448197 Free PMC article.
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