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Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus-neutralizing activity in vaccinated mice.
Dobrica MO, van Eerde A, Tucureanu C, Onu A, Paruch L, Caras I, Vlase E, Steen H, Haugslien S, Alonzi D, Zitzmann N, Bock R, Dubuisson J, Popescu CI, Stavaru C, Liu Clarke J, Branza-Nichita N. Dobrica MO, et al. Among authors: paruch l. Plant Biotechnol J. 2021 Oct;19(10):2027-2039. doi: 10.1111/pbi.13631. Epub 2021 Jun 3. Plant Biotechnol J. 2021. PMID: 34002936 Free PMC article.
In-depth characterization of Trichoderma reesei cellobiohydrolase TrCel7A produced in Nicotiana benthamiana reveals limitations of cellulase production in plants by host-specific post-translational modifications.
van Eerde A, Várnai A, Jameson JK, Paruch L, Moen A, Anonsen JH, Chylenski P, Steen HS, Heldal I, Bock R, Eijsink VGH, Liu-Clarke J. van Eerde A, et al. Among authors: paruch l. Plant Biotechnol J. 2020 Mar;18(3):631-643. doi: 10.1111/pbi.13227. Epub 2019 Aug 17. Plant Biotechnol J. 2020. PMID: 31373133 Free PMC article.
Lettuce-produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination.
Clarke JL, Paruch L, Dobrica MO, Caras I, Tucureanu C, Onu A, Ciulean S, Stavaru C, Eerde A, Wang Y, Steen H, Haugslien S, Petrareanu C, Lazar C, Popescu CI, Bock R, Dubuisson J, Branza-Nichita N. Clarke JL, et al. Among authors: paruch l. Plant Biotechnol J. 2017 Dec;15(12):1611-1621. doi: 10.1111/pbi.12743. Epub 2017 Jun 9. Plant Biotechnol J. 2017. PMID: 28419665 Free PMC article.
A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein.
Dobrica MO, Lazar C, Paruch L, Skomedal H, Steen H, Haugslien S, Tucureanu C, Caras I, Onu A, Ciulean S, Branzan A, Clarke JL, Stavaru C, Branza-Nichita N. Dobrica MO, et al. Among authors: paruch l. Antiviral Res. 2017 Aug;144:256-265. doi: 10.1016/j.antiviral.2017.06.017. Epub 2017 Jun 27. Antiviral Res. 2017. PMID: 28666757
Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice.
Dobrica MO, Lazar C, Paruch L, van Eerde A, Clarke JL, Tucureanu C, Caras I, Ciulean S, Onu A, Tofan V, Branzan A, Urban S, Stavaru C, Branza-Nichita N. Dobrica MO, et al. Among authors: paruch l. Vaccine. 2018 Sep 11;36(38):5789-5795. doi: 10.1016/j.vaccine.2018.07.072. Epub 2018 Aug 3. Vaccine. 2018. PMID: 30082163
20 results