Parvathy S - Search Results

1

Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline.

Parvathy S, Davies P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, Park H, Moran TM, Chan JY, Buxbaum JD. Parvathy S, et al. Arch Neurol. 2001 Dec;58(12):2025-32. doi: 10.1001/archneur.58.12.2025. Arch Neurol. 2001. PMID: 11735776

2

Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.

Parvathy S, Ehrlich M, Pedrini S, Diaz N, Refolo L, Buxbaum JD, Bogush A, Petanceska S, Gandy S. Parvathy S, et al. J Neurochem. 2004 Aug;90(4):1005-10. doi: 10.1111/j.1471-4159.2004.02521.x. J Neurochem. 2004. PMID: 15287907 Free article.

3

Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.

Parvathy S, Hussain I, Karran EH, Turner AJ, Hooper NM. Parvathy S, et al. Biochemistry. 1999 Jul 27;38(30):9728-34. doi: 10.1021/bi9906827. Biochemistry. 1999. PMID: 10423252

Parallel studies using an antibody that recognizes specifically the neoepitope revealed on soluble APP cleaved by beta-secretase indicated that this enzyme was acting intracellularly. alpha-Secretase is a zinc metalloproteinase susceptible to inhibition by hydroxamate-based compo …

Parallel studies using an antibody that recognizes specifically the neoepitope revealed on soluble APP cleaved by beta-secretase indicated t …

4

Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.

Parvathy S, Hussain I, Karran EH, Turner AJ, Hooper NM. Parvathy S, et al. Biochemistry. 1998 Feb 10;37(6):1680-5. doi: 10.1021/bi972034y. Biochemistry. 1998. PMID: 9484239

5

Gene expression profile of the PDAPP mouse model for Alzheimer's disease with and without Apolipoprotein E.

Selwood SP, Parvathy S, Cordell B, Ryan HS, Oshidari F, Vincent V, Yesavage J, Lazzeroni LC, Murphy GM Jr. Selwood SP, et al. Among authors: parvathy s. Neurobiol Aging. 2009 Apr;30(4):574-90. doi: 10.1016/j.neurobiolaging.2007.08.006. Epub 2007 Sep 29. Neurobiol Aging. 2009. PMID: 17904698

6

Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer.

Parvathy S, Oppong SY, Karran EH, Buckle DR, Turner AJ, Hooper NM. Parvathy S, et al. Biochem J. 1997 Oct 1;327 ( Pt 1)(Pt 1):37-43. doi: 10.1042/bj3270037. Biochem J. 1997. PMID: 9355732 Free PMC article.

7

The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors.

Parvathy S, Hussain I, Karran EH, Turner AJ, Hooper NM. Parvathy S, et al. Biochem Soc Trans. 1998 Aug;26(3):S242. doi: 10.1042/bst026s242. Biochem Soc Trans. 1998. PMID: 9765961 No abstract available.

8

Angiotensin-converting enzyme and the amyloid precursor protein secretases.

Hooper NM, Parvathy S, Karran EH, Turner AJ. Hooper NM, et al. Among authors: parvathy s. Biochem Soc Trans. 1999 Feb;27(2):229-34. doi: 10.1042/bst0270229. Biochem Soc Trans. 1999. PMID: 10093739 Review. No abstract available.

9

Inhibition of α-Secretase by Zinc Metalloproteinase Inhibitors.

Parvathy S, Turner AJ, Hooper NM. Parvathy S, et al. Methods Mol Med. 2000;32:203-15. doi: 10.1385/1-59259-195-7:203. Methods Mol Med. 2000. PMID: 21318520

10

The secretases that cleave angiotensin converting enzyme and the amyloid precursor protein are distinct from tumour necrosis factor-alpha convertase.

Parvathy S, Karran EH, Turner AJ, Hooper NM. Parvathy S, et al. FEBS Lett. 1998 Jul 10;431(1):63-5. doi: 10.1016/s0014-5793(98)00726-1. FEBS Lett. 1998. PMID: 9684866 Free article.

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