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The expression and environmental regulation of P450 enzymes in human placenta.
Pasanen M, Pelkonen O. Pasanen M, et al. Crit Rev Toxicol. 1994;24(3):211-29. doi: 10.3109/10408449409021606. Crit Rev Toxicol. 1994. PMID: 7945891 Review.
Lack of association between CYP2A5 induction and apoptosis in mouse primary hepatocytes.
Tetri S, Ruhanen M, Viitala P, Pelkonen O, Pasanen M, Raunio H. Tetri S, et al. Among authors: pasanen m. Biochem Pharmacol. 2002 Feb 1;63(3):429-35. doi: 10.1016/s0006-2952(01)00909-1. Biochem Pharmacol. 2002. PMID: 11853694
Diabetes and elimination of antipyrine in man: an analysis of 298 patients classified by type of diabetes, age, sex, duration of disease and liver involvement.
Sotaniemi EA, Pelkonen O, Arranto AJ, Tapanainen P, Rautio A, Pasanen M. Sotaniemi EA, et al. Among authors: pasanen m. Pharmacol Toxicol. 2002 Mar;90(3):155-60. doi: 10.1034/j.1600-0773.2002.900308.x. Pharmacol Toxicol. 2002. PMID: 12071338 Clinical Trial.
In silico prediction of the site of oxidation by cytochrome P450 3A4 that leads to the formation of the toxic metabolites of pyrrolizidine alkaloids.
Fashe MM, Juvonen RO, Petsalo A, Vepsäläinen J, Pasanen M, Rahnasto-Rilla M. Fashe MM, et al. Among authors: pasanen m. Chem Res Toxicol. 2015 Apr 20;28(4):702-10. doi: 10.1021/tx500478q. Epub 2015 Feb 17. Chem Res Toxicol. 2015. PMID: 25651456
The unique characteristics of the placental transcriptome and the hormonal metabolism enzymes in placenta.
Storvik M, Huuskonen P, Pehkonen P, Pasanen M. Storvik M, et al. Among authors: pasanen m. Reprod Toxicol. 2014 Aug;47:9-14. doi: 10.1016/j.reprotox.2014.04.010. Epub 2014 May 9. Reprod Toxicol. 2014. PMID: 24814680
Chloropicrin-induced toxic responses in human lung epithelial cells.
Pesonen M, Häkkinen M, Rilla K, Juvonen R, Kuitunen T, Pasanen M, Vähäkangas K. Pesonen M, et al. Among authors: pasanen m. Toxicol Lett. 2014 Apr 21;226(2):236-44. doi: 10.1016/j.toxlet.2014.02.006. Epub 2014 Feb 15. Toxicol Lett. 2014. PMID: 24548678
The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells.
Huuskonen P, Myllynen P, Storvik M, Pasanen M. Huuskonen P, et al. Among authors: pasanen m. Toxicol Lett. 2013 Apr 26;218(3):200-6. doi: 10.1016/j.toxlet.2013.01.015. Epub 2013 Feb 10. Toxicol Lett. 2013. PMID: 23402939
2'-Deoxyguanosine as a surrogate trapping agent for DNA reactive drug metabolites.
Häkkinen MR, Laine JE, Juvonen RO, Auriola S, Häyrinen J, Pasanen M. Häkkinen MR, et al. Among authors: pasanen m. Toxicol Lett. 2011 Nov 10;207(1):34-41. doi: 10.1016/j.toxlet.2011.08.020. Epub 2011 Sep 2. Toxicol Lett. 2011. PMID: 21907773
Aflatoxin B1--a potential endocrine disruptor--up-regulates CYP19A1 in JEG-3 cells.
Storvik M, Huuskonen P, Kyllönen T, Lehtonen S, El-Nezami H, Auriola S, Pasanen M. Storvik M, et al. Among authors: pasanen m. Toxicol Lett. 2011 May 10;202(3):161-7. doi: 10.1016/j.toxlet.2011.01.028. Epub 2011 Feb 4. Toxicol Lett. 2011. PMID: 21296134
The fate and effects of xenobiotics in human placenta.
Myllynen P, Pasanen M, Vähäkangas K. Myllynen P, et al. Among authors: pasanen m. Expert Opin Drug Metab Toxicol. 2007 Jun;3(3):331-46. doi: 10.1517/17425255.3.3.331. Expert Opin Drug Metab Toxicol. 2007. PMID: 17539742 Review.
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