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Characterization of a novel PXR isoform with potential dominant-negative properties.
Breuker C, Planque C, Rajabi F, Nault JC, Couchy G, Zucman-Rossi J, Evrard A, Kantar J, Chevet E, Bioulac-Sage P, Ramos J, Assenat E, Joubert D, Pannequin J, Hollande F, Pascussi JM. Breuker C, et al. Among authors: pascussi jm. J Hepatol. 2014 Sep;61(3):609-16. doi: 10.1016/j.jhep.2014.04.030. Epub 2014 May 2. J Hepatol. 2014. PMID: 24798619
Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, Goron A, Gamet-Payrastre L, Gerbal-Chaloin S, Pascussi JM, Moldes M, Pineau T, Guillou H, Mselli-Lakhal L. Marmugi A, et al. Among authors: pascussi jm. Toxicol Appl Pharmacol. 2016 Jul 15;303:90-100. doi: 10.1016/j.taap.2016.05.006. Epub 2016 May 11. Toxicol Appl Pharmacol. 2016. PMID: 27180240
Pathophysiological factors affecting CAR gene expression.
Pascussi JM, Dvorák Z, Gerbal-Chaloin S, Assenat E, Maurel P, Vilarem MJ. Pascussi JM, et al. Drug Metab Rev. 2003 Nov;35(4):255-68. doi: 10.1081/dmr-120026394. Drug Metab Rev. 2003. PMID: 14705859 Review.
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