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Page 1
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis.
Seidman JS, Troutman TD, Sakai M, Gola A, Spann NJ, Bennett H, Bruni CM, Ouyang Z, Li RZ, Sun X, Vu BT, Pasillas MP, Ego KM, Gosselin D, Link VM, Chong LW, Evans RM, Thompson BM, McDonald JG, Hosseini M, Witztum JL, Germain RN, Glass CK. Seidman JS, et al. Among authors: pasillas mp. Immunity. 2020 Jun 16;52(6):1057-1074.e7. doi: 10.1016/j.immuni.2020.04.001. Epub 2020 May 1. Immunity. 2020. PMID: 32362324 Free PMC article.
An environment-dependent transcriptional network specifies human microglia identity.
Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. Gosselin D, et al. Among authors: pasillas mp. Science. 2017 Jun 23;356(6344):eaal3222. doi: 10.1126/science.aal3222. Epub 2017 May 25. Science. 2017. PMID: 28546318 Free PMC article.
Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.
Sakai M, Troutman TD, Seidman JS, Ouyang Z, Spann NJ, Abe Y, Ego KM, Bruni CM, Deng Z, Schlachetzki JCM, Nott A, Bennett H, Chang J, Vu BT, Pasillas MP, Link VM, Texari L, Heinz S, Thompson BM, McDonald JG, Geissmann F, Glass CK. Sakai M, et al. Among authors: pasillas mp. Immunity. 2019 Oct 15;51(4):655-670.e8. doi: 10.1016/j.immuni.2019.09.002. Epub 2019 Oct 3. Immunity. 2019. PMID: 31587991 Free PMC article.
Brain cell type-specific enhancer-promoter interactome maps and disease-risk association.
Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. Nott A, et al. Among authors: pasillas mp. Science. 2019 Nov 29;366(6469):1134-1139. doi: 10.1126/science.aay0793. Epub 2019 Nov 14. Science. 2019. PMID: 31727856 Free PMC article.
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.
Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. Sun X, et al. Cell Metab. 2020 Jan 7;31(1):189-206.e8. doi: 10.1016/j.cmet.2019.10.014. Epub 2019 Nov 21. Cell Metab. 2020. PMID: 31761566 Free PMC article.
Heterogeneity of HSCs in a Mouse Model of NASH.
Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. Rosenthal SB, et al. Among authors: pasillas mp. Hepatology. 2021 Aug;74(2):667-685. doi: 10.1002/hep.31743. Epub 2021 Aug 10. Hepatology. 2021. PMID: 33550587 Free PMC article.
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.
Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK. Fixsen BR, et al. Among authors: pasillas mp. Nat Immunol. 2023 Jul;24(7):1188-1199. doi: 10.1038/s41590-023-01528-8. Epub 2023 Jun 15. Nat Immunol. 2023. PMID: 37322178 Free PMC article.
Human microglia maturation is underpinned by specific gene regulatory networks.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA; Birth Defects Research Laboratory; Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. Han CZ, et al. Among authors: pasillas mp. Immunity. 2023 Sep 12;56(9):2152-2171.e13. doi: 10.1016/j.immuni.2023.07.016. Epub 2023 Aug 14. Immunity. 2023. PMID: 37582369 Free article.
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes.
Bennett H, Troutman TD, Zhou E, Spann NJ, Link VM, Seidman JS, Nickl CK, Abe Y, Sakai M, Pasillas MP, Marlman JM, Guzman C, Hosseini M, Schnabl B, Glass CK. Bennett H, et al. Among authors: pasillas mp. Nat Immunol. 2023 Nov;24(11):1825-1838. doi: 10.1038/s41590-023-01631-w. Epub 2023 Sep 21. Nat Immunol. 2023. PMID: 37735593 Free PMC article.
Somatic mosaicism reveals clonal distributions of neocortical development.
Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y; NIMH Brain Somatic Mosaicism Network; Glass CK, Gleeson JG. Breuss MW, et al. Among authors: pasillas mp. Nature. 2022 Apr;604(7907):689-696. doi: 10.1038/s41586-022-04602-7. Epub 2022 Apr 20. Nature. 2022. PMID: 35444276 Free PMC article.
26 results