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Molecular interactions in extracellular matrix of tendon.
Karousou E, Ronga M, Vigetti D, Barcolli D, Passi A, Maffulli N. Karousou E, et al. Front Biosci (Elite Ed). 2010 Jan 1;2:1-12. doi: 10.2741/e59. Front Biosci (Elite Ed). 2010. PMID: 20036847 Review.
Tendon is a poorly vascularized and highly specialized connective tissue containing few scattered cells that play an important role in the musculoskeletal apparatus by resisting mechanical stress. ...
Tendon is a poorly vascularized and highly specialized connective tissue containing few scattered cells that play an important role i …
The effect of glycosaminoglycans and proteoglycans on lipid peroxidation.
Albertini R, Passi A, Abuja PM, De Luca G. Albertini R, et al. Int J Mol Med. 2000 Aug;6(2):129-36. doi: 10.3892/ijmm.6.2.129. Int J Mol Med. 2000. PMID: 10891555 Review.
The mechanism of peroxidation inhibition was likely to be dependent, at least to a large extent, on the sequestration of transition metals by GAG chains. ...It is of particular interest that in certain tissues (cornea and aorta) aging was associated with a decrease …
The mechanism of peroxidation inhibition was likely to be dependent, at least to a large extent, on the sequestration of transition m …
Development of lung edema: interstitial fluid dynamics and molecular structure.
Miserocchi G, Negrini D, Passi A, De Luca G. Miserocchi G, et al. News Physiol Sci. 2001 Apr;16:66-71. doi: 10.1152/physiologyonline.2001.16.2.66. News Physiol Sci. 2001. PMID: 11390951 Review.
Application of polyacrylamide gel electrophoresis of fluorophore-labeled saccharides for analysis of hyaluronan and chondroitin sulfate in human and animal tissues and cell cultures.
Karousou EG, Viola M, Genasetti A, Vigetti D, Luca GD, Karamanos NK, Passi A. Karousou EG, et al. Biomed Chromatogr. 2005 Dec;19(10):761-5. doi: 10.1002/bmc.511. Biomed Chromatogr. 2005. PMID: 15856490
Moreover, also in Xenopus laevis embryo development and chondrocyte cultures, the GAG content and structure play a critical role. ...Since this method allows the analysis of large numbers of samples simultaneously in one gel and has a relatively high sensitivity (le …
Moreover, also in Xenopus laevis embryo development and chondrocyte cultures, the GAG content and structure play a critical role. ... …
Differential degradation of matrix proteoglycans and edema development in rabbit lung.
Negrini D, Tenstad O, Passi A, Wiig H. Negrini D, et al. Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L470-7. doi: 10.1152/ajplung.00310.2005. Epub 2005 Oct 7. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16214813
With respect to control (Pip= -9.3 +/- 1.5 cmH2O, n = 10), both treatments caused a significant increase of Pip and of the wet weight-to-dry weight lung ratio. ...Biochemical analysis performed on a separate rabbit group (n = 15) showed an increased extraction of ur …
With respect to control (Pip= -9.3 +/- 1.5 cmH2O, n = 10), both treatments caused a significant increase of Pip and of the wet weight …
Decorin from different bovine tissues: study of glycosaminoglycan chain by PAGEFS.
Viola M, Karousou EG, Vigetti D, Genasetti A, Pallotti F, Guidetti GF, Tira E, De Luca G, Passi A. Viola M, et al. J Pharm Biomed Anal. 2006 Apr 11;41(1):36-42. doi: 10.1016/j.jpba.2005.10.010. Epub 2005 Nov 15. J Pharm Biomed Anal. 2006. PMID: 16293388
The sulphation pattern of glycosaminoglycan (GAG) plays a critical role in biological functions of proteoglycans. In this study, we showed that decorins from different bovine tissues present specific sulphation pattern coupled with peculiar biological activity. ...This app …
The sulphation pattern of glycosaminoglycan (GAG) plays a critical role in biological functions of proteoglycans. In this study, we s …
Matrix metalloproteinase 2 and tissue inhibitors of metalloproteinases regulate human aortic smooth muscle cell migration during in vitro aging.
Vigetti D, Moretto P, Viola M, Genasetti A, Rizzi M, Karousou E, Pallotti F, De Luca G, Passi A. Vigetti D, et al. FASEB J. 2006 Jun;20(8):1118-30. doi: 10.1096/fj.05-4504com. FASEB J. 2006. PMID: 16770011
As a direct correlation between aging and the risk of onset of vascular disease has been universally accepted, we prepared an in vitro aging model consisting in sequential passages of human aortic smooth muscle cells (AoSMC) in order to evaluate the cell behavior changes d …
As a direct correlation between aging and the risk of onset of vascular disease has been universally accepted, we prepared an in vitr …
Interstitial matrix and transendothelial fluxes in normal lung.
Negrini D, Passi A. Negrini D, et al. Respir Physiol Neurobiol. 2007 Dec 15;159(3):301-10. doi: 10.1016/j.resp.2007.04.003. Epub 2007 Apr 8. Respir Physiol Neurobiol. 2007. PMID: 17499562 Review.
The integrity of the macromolecular assembly of the tissue matrix is required in all processes involved in establishing and maintaining the adequate interstitial tissue fluid volume, by providing: (a) a stiff three dimensional fibrous scaffold, functioning as an eff …
The integrity of the macromolecular assembly of the tissue matrix is required in all processes involved in establishing and maintaining the …
The extracellular matrix of the lung and its role in edema formation.
Pelosi P, Rocco PR, Negrini D, Passi A. Pelosi P, et al. An Acad Bras Cienc. 2007 Jun;79(2):285-97. doi: 10.1590/s0001-37652007000200010. An Acad Bras Cienc. 2007. PMID: 17625682 Review.
Conversely, a massive matrix deposition of collagen fiber decreases interstitial compliance and therefore makes the tissue safety factor stronger. As a result, changes in lung extracellular matrix significantly affect edema formation and distribution in the lung....
Conversely, a massive matrix deposition of collagen fiber decreases interstitial compliance and therefore makes the tissue safety fac …
The role of proteoglycans in pulmonary edema development.
Negrini D, Passi A, Moriondo A. Negrini D, et al. Intensive Care Med. 2008 Apr;34(4):610-8. doi: 10.1007/s00134-007-0962-y. Epub 2008 Feb 9. Intensive Care Med. 2008. PMID: 18264693 Review.
The fibrous ECM components, in particular the chondroitin sulfate proteoglycan (CS-PG) and the heparan-sulfate proteoglycan (HS-PG) families, play a major role in the maintenance of tissue fluid homeostasis. In fact, they provide: (a) a perivascular and inter …
The fibrous ECM components, in particular the chondroitin sulfate proteoglycan (CS-PG) and the heparan-sulfate proteoglycan (HS-PG) families …
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