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Page 1
Immunotoxin therapy for cancer.
Pai LH, Pastan I. Pai LH, et al. Among authors: pastan i. JAMA. 1993 Jan 6;269(1):78-81. JAMA. 1993. PMID: 8416411 Review. No abstract available.
Targeting growth factor receptors with fusion toxins.
Kreitman RJ, FitzGerald D, Pastan I. Kreitman RJ, et al. Among authors: pastan i. Int J Immunopharmacol. 1992 Apr;14(3):465-72. doi: 10.1016/0192-0561(92)90177-m. Int J Immunopharmacol. 1992. PMID: 1319965 Review.
In vitro effects of a recombinant toxin targeted to the fibroblast growth factor receptor on rat vascular smooth muscle and endothelial cells.
Biro S, Siegall CB, Fu YM, Speir E, Pastan I, Epstein SE. Biro S, et al. Among authors: pastan i. Circ Res. 1992 Sep;71(3):640-5. doi: 10.1161/01.res.71.3.640. Circ Res. 1992. PMID: 1323436
A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies.
Buchner J, Pastan I, Brinkmann U. Buchner J, et al. Among authors: pastan i. Anal Biochem. 1992 Sep;205(2):263-70. doi: 10.1016/0003-2697(92)90433-8. Anal Biochem. 1992. PMID: 1332541
Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.
Batra JK, Kasprzyk PG, Bird RE, Pastan I, King CR. Batra JK, et al. Among authors: pastan i. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5867-71. doi: 10.1073/pnas.89.13.5867. Proc Natl Acad Sci U S A. 1992. PMID: 1352878 Free PMC article.
Monoclonal antibody MRK16 reverses the multidrug resistance of multidrug-resistant transgenic mice.
Mickisch GH, Pai LH, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. Cancer Res. 1992 Aug 15;52(16):4427-32. Cancer Res. 1992. PMID: 1353705
Renaturation of a single-chain immunotoxin facilitated by chaperones and protein disulfide isomerase.
Buchner J, Brinkmann U, Pastan I. Buchner J, et al. Among authors: pastan i. Biotechnology (N Y). 1992 Jun;10(6):682-5. doi: 10.1038/nbt0692-682. Biotechnology (N Y). 1992. PMID: 1369490
Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells.
Merwin JR, Lynch MJ, Madri JA, Pastan I, Siegall CB. Merwin JR, et al. Among authors: pastan i. Cancer Res. 1992 Sep 15;52(18):4995-5001. Cancer Res. 1992. PMID: 1381275
RFCs were also cultured in a 3-dimensional type I collagen gel and incubated with either transforming growth factor beta 1, aFGF-PE, or a combination of both. ...
RFCs were also cultured in a 3-dimensional type I collagen gel and incubated with either transforming growth factor beta 1, aFGF-PE, …
Monovalent immunotoxin containing truncated form of Pseudomonas exotoxin as potent antitumor agent.
Debinski W, Pastan I. Debinski W, et al. Among authors: pastan i. Cancer Res. 1992 Oct 1;52(19):5379-85. Cancer Res. 1992. PMID: 1394141
Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor.
Kreitman RJ, Schneider WP, Queen C, Tsudo M, Fitzgerald DJ, Waldmann TA, Pastan I. Kreitman RJ, et al. Among authors: pastan i. J Immunol. 1992 Oct 15;149(8):2810-5. J Immunol. 1992. PMID: 1401913
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