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Page 1
Recent Advancement of Medical Patch for Transdermal Drug Delivery.
Wong WF, Ang KP, Sethi G, Looi CY. Wong WF, et al. Medicina (Kaunas). 2023 Apr 17;59(4):778. doi: 10.3390/medicina59040778. Medicina (Kaunas). 2023. PMID: 37109736 Free PMC article. Review.
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a specific dose of medication through the skin and into the bloodstream throughout the body. ...Recently, this method is also being explor …
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a spe …
Microneedles for advanced ocular drug delivery.
Glover K, Mishra D, Gade S, Vora LK, Wu Y, Paredes AJ, Donnelly RF, Singh TRR. Glover K, et al. Adv Drug Deliv Rev. 2023 Oct;201:115082. doi: 10.1016/j.addr.2023.115082. Epub 2023 Sep 9. Adv Drug Deliv Rev. 2023. PMID: 37678648 Free article. Review.
As a result, there is a clear unmet need for sustained drug delivery to the eye, particularly in a manner that can be localised. Microneedles, which are patches containing an array of micron-scale needles (<1 mm), have the potential to meet this need. ...Considering the …
As a result, there is a clear unmet need for sustained drug delivery to the eye, particularly in a manner that can be localised. Microneedle …
Abuse of fentanyl: An emerging problem to face.
Kuczyńska K, Grzonkowski P, Kacprzak Ł, Zawilska JB. Kuczyńska K, et al. Forensic Sci Int. 2018 Aug;289:207-214. doi: 10.1016/j.forsciint.2018.05.042. Epub 2018 Jun 2. Forensic Sci Int. 2018. PMID: 29902699 Review.
The other way to gain fentanyl is through the diversion of fentanyl-containing medicines, especially transdermal patches (FTPs). Fentanyl extracted from FTP can be administered intravenously, insufflated or inhaled after volatilization. The drug can also be delivered …
The other way to gain fentanyl is through the diversion of fentanyl-containing medicines, especially transdermal patches (FTPs). Fent …
Transdermal patches: Design and current approaches to painless drug delivery.
Al Hanbali OA, Khan HMS, Sarfraz M, Arafat M, Ijaz S, Hameed A. Al Hanbali OA, et al. Acta Pharm. 2019 Jun 1;69(2):197-215. doi: 10.2478/acph-2019-0016. Acta Pharm. 2019. PMID: 31259729 Free article. Review.
Although transdermal patches have medical applications for smoking cessation, pain relief, osteoporosis, contraception, motion sickness, angina pectoris, and cardiac disorders, advances in formulation development are ongoing to make transdermal patches capabl …
Although transdermal patches have medical applications for smoking cessation, pain relief, osteoporosis, contraception, motion …
Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome.
Lee Y, Kamada N, Moon JJ. Lee Y, et al. Adv Drug Deliv Rev. 2021 Dec;179:114021. doi: 10.1016/j.addr.2021.114021. Epub 2021 Oct 26. Adv Drug Deliv Rev. 2021. PMID: 34710529 Free PMC article. Review.
With the advances of novel nanomaterials, oral nanomedicine has emerged as an attractive option to not only overcome these barriers but also to selectively deliver drugs to the target sites in GIT. In this review, we discuss the GIT factors and physicochemical and biologic …
With the advances of novel nanomaterials, oral nanomedicine has emerged as an attractive option to not only overcome these barriers but also …
Microneedle Patch Loaded with Exosomes Containing MicroRNA-29b Prevents Cardiac Fibrosis after Myocardial Infarction.
Yuan J, Yang H, Liu C, Shao L, Zhang H, Lu K, Wang J, Wang Y, Yu Q, Zhang Y, Yu Y, Shen Z. Yuan J, et al. Adv Healthc Mater. 2023 May;12(13):e2202959. doi: 10.1002/adhm.202202959. Epub 2023 Feb 5. Adv Healthc Mater. 2023. PMID: 36739582
To this end, a biocompatible microneedle (MN) patch based on gelatin is fabricated to load exosomes containing microRNA-29b (miR-29b) mimics with antifibrotic activity to prevent excessive cardiac fibrosis after MI. ...This design explored the MN patch as a suitable …
To this end, a biocompatible microneedle (MN) patch based on gelatin is fabricated to load exosomes containing microRNA-29b (miR-29b) …
Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues.
Spang MT, Middleton R, Diaz M, Hunter J, Mesfin J, Banka A, Sullivan H, Wang R, Lazerson TS, Bhatia S, Corbitt J, D'Elia G, Sandoval-Gomez G, Kandell R, Vratsanos MA, Gnanasekaran K, Kato T, Igata S, Luo C, Osborn KG, Gianneschi NC, Eniola-Adefeso O, Cabrales P, Kwon EJ, Contijoch F, Reeves RR, DeMaria AN, Christman KL. Spang MT, et al. Nat Biomed Eng. 2023 Feb;7(2):94-109. doi: 10.1038/s41551-022-00964-5. Epub 2022 Dec 29. Nat Biomed Eng. 2023. PMID: 36581694 Free PMC article.
Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal models of disease. ...In rats and pigs with induced acute myocardial infarction followed by intracoronary infusion of the biomaterial, we obs …
Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal m …
Hydrogel Microneedle Patches Loaded with Stem Cell Mitochondria-Enriched Microvesicles Boost the Chronic Wound Healing.
Yao WD, Zhou JN, Tang C, Zhang JL, Chen ZY, Li Y, Gong XJ, Qu MY, Zeng Q, Jia YL, Wang HY, Fan T, Ren J, Guo LL, Xi JF, Pei XT, Han Y, Yue W. Yao WD, et al. ACS Nano. 2024 Oct 1;18(39):26733-26750. doi: 10.1021/acsnano.4c06921. Epub 2024 Sep 5. ACS Nano. 2024. PMID: 39238258 Free PMC article.
Thus, in this study, we aimed to design an effective hydrogel microneedle patch (MNP) loaded with stem cell-derived mitochondria-rich EVs to gradually release and deliver mitochondria into the wound tissues and boost wound healing. ...Collectively, we successfully f …
Thus, in this study, we aimed to design an effective hydrogel microneedle patch (MNP) loaded with stem cell-derived mitochondria-rich …
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair.
Zhu D, Li Z, Huang K, Caranasos TG, Rossi JS, Cheng K. Zhu D, et al. Nat Commun. 2021 Mar 3;12(1):1412. doi: 10.1038/s41467-021-21682-7. Nat Commun. 2021. PMID: 33658506 Free PMC article.
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such procedures are normally invasive and difficult to perform. ...Collectively, our study establishes intrapericardial injection as a safe and effective method to deliver the …
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such procedures are normally invasive and …
Characteristics of Analgesic Patch Formulations.
Nalamachu S, Gudin J. Nalamachu S, et al. J Pain Res. 2020 Sep 22;13:2343-2354. doi: 10.2147/JPR.S270169. eCollection 2020. J Pain Res. 2020. PMID: 33061549 Free PMC article. Review.
One method of drug delivery is with the use of patch formulations - also known as patch systems. Typically, transdermal patches deliver medications intended to reach the systemic circulation, whereas topical patches are designed to keep …
One method of drug delivery is with the use of patch formulations - also known as patch systems. Typically, transdermal pat …
1,206 results