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10,148 results
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A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
Patel A, Vought VE, Dharmarajan V, Cosgrove MS. Patel A, et al. J Biol Chem. 2008 Nov 21;283(47):32162-75. doi: 10.1074/jbc.M806317200. Epub 2008 Oct 1. J Biol Chem. 2008. PMID: 18829457
Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
Patel A, Dharmarajan V, Cosgrove MS. Patel A, et al. J Biol Chem. 2008 Nov 21;283(47):32158-61. doi: 10.1074/jbc.C800164200. Epub 2008 Oct 1. J Biol Chem. 2008. PMID: 18829459
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A, Dharmarajan V, Vought VE, Cosgrove MS. Patel A, et al. J Biol Chem. 2009 Sep 4;284(36):24242-56. doi: 10.1074/jbc.M109.014498. Epub 2009 Jun 25. J Biol Chem. 2009. PMID: 19556245 Free PMC article.
Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.
Cosgrove MS, Patel A. Cosgrove MS, et al. Among authors: patel a. FEBS J. 2010 Apr;277(8):1832-42. doi: 10.1111/j.1742-4658.2010.07609.x. Epub 2010 Mar 4. FEBS J. 2010. PMID: 20236310 Free PMC article. Review.
A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A, Vought VE, Dharmarajan V, Cosgrove MS. Patel A, et al. J Biol Chem. 2011 Feb 4;286(5):3359-69. doi: 10.1074/jbc.M110.174524. Epub 2010 Nov 24. J Biol Chem. 2011. PMID: 21106533 Free PMC article.
Myosin5a tail associates directly with Rab3A-containing compartments in neurons.
Wöllert T, Patel A, Lee YL, Provance DW Jr, Vought VE, Cosgrove MS, Mercer JA, Langford GM. Wöllert T, et al. Among authors: patel a. J Biol Chem. 2011 Apr 22;286(16):14352-61. doi: 10.1074/jbc.M110.187286. Epub 2011 Feb 23. J Biol Chem. 2011. PMID: 21349835 Free PMC article.
Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination.
Mbantenkhu M, Wang X, Nardozzi JD, Wilkens S, Hoffman E, Patel A, Cosgrove MS, Chen XJ. Mbantenkhu M, et al. Among authors: patel a. J Biol Chem. 2011 Dec 9;286(49):42360-70. doi: 10.1074/jbc.M111.307512. Epub 2011 Oct 25. J Biol Chem. 2011. PMID: 22027892 Free PMC article.
Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.
Zhong S, Hsu F, Stefan CJ, Wu X, Patel A, Cosgrove MS, Mao Y. Zhong S, et al. Among authors: patel a. Biochemistry. 2012 Apr 17;51(15):3170-7. doi: 10.1021/bi300086c. Epub 2012 Apr 3. Biochemistry. 2012. PMID: 22452743 Free PMC article.
Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
Dharmarajan V, Lee JH, Patel A, Skalnik DG, Cosgrove MS. Dharmarajan V, et al. Among authors: patel a. J Biol Chem. 2012 Aug 10;287(33):27275-89. doi: 10.1074/jbc.M112.364125. Epub 2012 Jun 3. J Biol Chem. 2012. PMID: 22665483 Free PMC article.
Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS. Patel A, et al. J Biol Chem. 2014 Jan 10;289(2):868-84. doi: 10.1074/jbc.M113.501064. Epub 2013 Nov 14. J Biol Chem. 2014. PMID: 24235145 Free PMC article.
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