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Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.
Dhillon S, Witteveldt J, Gatherer D, Owsianka AM, Zeisel MB, Zahid MN, Rychłowska M, Foung SK, Baumert TF, Angus AG, Patel AH. Dhillon S, et al. Among authors: patel ah. J Virol. 2010 Jun;84(11):5494-507. doi: 10.1128/JVI.02153-09. Epub 2010 Mar 17. J Virol. 2010. PMID: 20237087 Free PMC article.
KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C.
Naiyer MM, Cassidy SA, Magri A, Cowton V, Chen K, Mansour S, Kranidioti H, Mbiribindi B, Rettman P, Harris S, Fanning LJ, Mulder A, Claas FHJ, Davidson AD, Patel AH, Purbhoo MA, Khakoo SI. Naiyer MM, et al. Among authors: patel ah. Sci Immunol. 2017 Sep 15;2(15):eaal5296. doi: 10.1126/sciimmunol.aal5296. Sci Immunol. 2017. PMID: 28916719
Interferon lambda 4 impacts the genetic diversity of hepatitis C virus.
Ansari MA, Aranday-Cortes E, Ip CL, da Silva Filipe A, Lau SH, Bamford C, Bonsall D, Trebes A, Piazza P, Sreenu V, Cowton VM; STOP-HCV Consortium; Hudson E, Bowden R, Patel AH, Foster GR, Irving WL, Agarwal K, Thomson EC, Simmonds P, Klenerman P, Holmes C, Barnes E, Spencer CC, McLauchlan J, Pedergnana V. Ansari MA, et al. Among authors: patel ah. Elife. 2019 Sep 3;8:e42463. doi: 10.7554/eLife.42463. Elife. 2019. PMID: 31478835 Free PMC article.
245 results