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Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4.
Girdhar A, Bharathi V, Tiwari VR, Abhishek S, Deeksha W, Mahawar US, Raju G, Singh SK, Prabusankar G, Rajakumara E, Patel BK. Girdhar A, et al. Among authors: patel bk. Int J Biol Macromol. 2020 Mar 15;147:117-130. doi: 10.1016/j.ijbiomac.2020.01.032. Epub 2020 Jan 7. Int J Biol Macromol. 2020. PMID: 31917988
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