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10,333 results
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Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer.
Patel S, Player MR. Patel S, et al. Expert Opin Investig Drugs. 2008 Dec;17(12):1865-82. doi: 10.1517/13543780802493366. Expert Opin Investig Drugs. 2008. PMID: 19012502 Review.
Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors.
Meegalla SK, Huang H, Illig CR, Parks DJ, Chen J, Lee YK, Wilson KJ, Patel SK, Cheung WS, Lu T, Kirchner T, Askari HB, Geisler J, Patch RJ, Gibbs AC, Rady B, Connelly M, Player MR. Meegalla SK, et al. Among authors: patel sk. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4216-22. doi: 10.1016/j.bmcl.2016.07.054. Epub 2016 Jul 25. Bioorg Med Chem Lett. 2016. PMID: 27491708
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif.
Kreutter KD, Lu T, Lee L, Giardino EC, Patel S, Huang H, Xu G, Fitzgerald M, Haertlein BJ, Mohan V, Crysler C, Eisennagel S, Dasgupta M, McMillan M, Spurlino JC, Huebert ND, Maryanoff BE, Tomczuk BE, Damiano BP, Player MR. Kreutter KD, et al. Among authors: patel s. Bioorg Med Chem Lett. 2008 May 1;18(9):2865-70. doi: 10.1016/j.bmcl.2008.03.087. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18420408
Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents.
Patch RJ, Huang H, Patel S, Cheung W, Xu G, Zhao BP, Beauchamp DA, Rentzeperis D, Geisler JG, Askari HB, Liu J, Kasturi J, Towers M, Gaul MD, Player MR. Patch RJ, et al. Among authors: patel s. Eur J Med Chem. 2017 Sep 29;138:830-853. doi: 10.1016/j.ejmech.2017.07.015. Epub 2017 Jul 14. Eur J Med Chem. 2017. PMID: 28735214
Series optimization provided several potent analogues that inhibited the recruitment of a co-activator peptide fragment in vitro (IC(50)s < 50 nM) and reduced fasted circulating insulin and triglyceride levels in a sub-chronic pre-diabetic rat model when administered or …
Series optimization provided several potent analogues that inhibited the recruitment of a co-activator peptide fragment in vitro (IC(50)s
Informal carers and peer support in pulmonary rehabilitation: an underutilized resource?
Patel S, Man WD, Roberts NJ. Patel S, et al. Curr Opin Support Palliat Care. 2020 Jul 23. doi: 10.1097/SPC.0000000000000517. Online ahead of print. Curr Opin Support Palliat Care. 2020. PMID: 32740276
Understanding COVID-19 Vaccines and Their Development.
Patel SS, Kalma J, Bluman EM. Patel SS, et al. J Bone Joint Surg Am. 2020 Jul 31. doi: 10.2106/JBJS.20.01191. Online ahead of print. J Bone Joint Surg Am. 2020. PMID: 32740262 No abstract available.
Ocular trauma during COVID-19 stay-at-home orders: a comparative cohort study.
Wu C, Patel SN, Jenkins TL, Obeid A, Ho AC, Yonekawa Y. Wu C, et al. Among authors: patel sn. Curr Opin Ophthalmol. 2020 Jul 27. doi: 10.1097/ICU.0000000000000687. Online ahead of print. Curr Opin Ophthalmol. 2020. PMID: 32740065
Reply.
Patel SV, Hodge DO, Treichel EJ, Spiegel MR, Baratz KH. Patel SV, et al. Ophthalmology. 2020 Jul 29:S0161-6420(20)30420-6. doi: 10.1016/j.ophtha.2020.04.042. Online ahead of print. Ophthalmology. 2020. PMID: 32739194 No abstract available.
Serratus Anterior Plane Block-A Promising Technique for Regional Anesthesia in Minimally Invasive Cardiac Surgery.
Patel SJ, Augoustides JGT. Patel SJ, et al. J Cardiothorac Vasc Anesth. 2020 Jul 11:S1053-0770(20)30641-8. doi: 10.1053/j.jvca.2020.07.011. Online ahead of print. J Cardiothorac Vasc Anesth. 2020. PMID: 32739085 No abstract available.
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