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The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study.
Paterson BM, Lammers KM, Arrieta MC, Fasano A, Meddings JB. Paterson BM, et al. Aliment Pharmacol Ther. 2007 Sep 1;26(5):757-66. doi: 10.1111/j.1365-2036.2007.03413.x. Aliment Pharmacol Ther. 2007. PMID: 17697209 Clinical Trial.
Effect of memantine on cough reflex sensitivity: translational studies in guinea pigs and humans.
Dicpinigaitis PV, Canning BJ, Garner R, Paterson B. Dicpinigaitis PV, et al. Among authors: paterson b. J Pharmacol Exp Ther. 2015 Mar;352(3):448-54. doi: 10.1124/jpet.114.221218. Epub 2014 Dec 18. J Pharmacol Exp Ther. 2015. PMID: 25525191 Clinical Trial.
Commentary: larazotide acetate - an exciting new development for coeliac patients? Authors' reply.
Kelly CP, Green PH, Murray JA, Dimarino A, Colatrella A, Leffler DA, Alexander T, Arsenescu R, Leon F, Jiang JG, Arterburn LA, Paterson BM, Fedorak RN; Larazotide Acetate Celiac Disease Study Group. Kelly CP, et al. Among authors: paterson bm. Aliment Pharmacol Ther. 2013 Feb;37(4):496-7. doi: 10.1111/apt.12196. Aliment Pharmacol Ther. 2013. PMID: 23336684 No abstract available.
Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study.
Kelly CP, Green PH, Murray JA, Dimarino A, Colatrella A, Leffler DA, Alexander T, Arsenescu R, Leon F, Jiang JG, Arterburn LA, Paterson BM, Fedorak RN; Larazotide Acetate Celiac Disease Study Group. Kelly CP, et al. Among authors: paterson bm. Aliment Pharmacol Ther. 2013 Jan;37(2):252-62. doi: 10.1111/apt.12147. Epub 2012 Nov 19. Aliment Pharmacol Ther. 2013. PMID: 23163616 Clinical Trial.
Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer.
Gopalakrishnan S, Pandey N, Tamiz AP, Vere J, Carrasco R, Somerville R, Tripathi A, Ginski M, Paterson BM, Alkan SS. Gopalakrishnan S, et al. Among authors: paterson bm. Int J Pharm. 2009 Jan 5;365(1-2):121-30. doi: 10.1016/j.ijpharm.2008.08.047. Epub 2008 Sep 11. Int J Pharm. 2009. PMID: 18832018
Larazotide acetate regulates epithelial tight junctions in vitro and in vivo.
Gopalakrishnan S, Durai M, Kitchens K, Tamiz AP, Somerville R, Ginski M, Paterson BM, Murray JA, Verdu EF, Alkan SS, Pandey NB. Gopalakrishnan S, et al. Among authors: paterson bm. Peptides. 2012 May;35(1):86-94. doi: 10.1016/j.peptides.2012.02.015. Epub 2012 Feb 27. Peptides. 2012. PMID: 22401908
A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge.
Leffler DA, Kelly CP, Abdallah HZ, Colatrella AM, Harris LA, Leon F, Arterburn LA, Paterson BM, Lan ZH, Murray JA. Leffler DA, et al. Among authors: paterson bm. Am J Gastroenterol. 2012 Oct;107(10):1554-62. doi: 10.1038/ajg.2012.211. Epub 2012 Jul 24. Am J Gastroenterol. 2012. PMID: 22825365 Free PMC article. Clinical Trial.
Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective N-methyl-D-aspartate receptor antagonist.
Garner R, Gopalakrishnan S, McCauley JA, Bednar RA, Gaul SL, Mosser SD, Kiss L, Lynch JJ, Patel S, Fandozzi C, Lagrutta A, Briscoe R, Liverton NJ, Paterson BM, Vornov JJ, Mazhari R. Garner R, et al. Among authors: paterson bm. Pharmacol Res Perspect. 2015 Dec 23;3(6):e00198. doi: 10.1002/prp2.198. eCollection 2015 Dec. Pharmacol Res Perspect. 2015. PMID: 27022470 Free PMC article. Review.
A randomized, double-blind, placebo-controlled study of the kappa opioid receptor antagonist, CERC-501, in a human laboratory model of smoking behavior.
Jones JD, Babalonis S, Marcus R, Vince B, Kelsh D, Lofwall MR, Fraser H, Paterson B, Martinez S, Martinez DM, Nunes EV, Walsh SL, Comer SD. Jones JD, et al. Among authors: paterson b. Addict Biol. 2020 Jul;25(4):e12799. doi: 10.1111/adb.12799. Epub 2019 Jun 26. Addict Biol. 2020. PMID: 31240842
Modification of Biodistribution and Brain Uptake of Copper Bis(thiosemicarbazonato) Complexes by the Incorporation of Amine and Polyamine Functional Groups.
Paterson BM, Cullinane C, Crouch PJ, White AR, Barnham KJ, Roselt PD, Noonan W, Binns D, Hicks RJ, Donnelly PS. Paterson BM, et al. Inorg Chem. 2019 Apr 1;58(7):4540-4552. doi: 10.1021/acs.inorgchem.9b00117. Epub 2019 Mar 14. Inorg Chem. 2019. PMID: 30869878
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