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Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.
Willems AR, Lanker S, Patton EE, Craig KL, Nason TF, Mathias N, Kobayashi R, Wittenberg C, Tyers M. Willems AR, et al. Cell. 1996 Aug 9;86(3):453-63. doi: 10.1016/s0092-8674(00)80118-x. Cell. 1996. PMID: 8756727
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.
Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M. Patton EE, et al. Genes Dev. 1998 Mar 1;12(5):692-705. doi: 10.1101/gad.12.5.692. Genes Dev. 1998. PMID: 9499404 Free PMC article.
Yeast G1 cyclins are unstable in G1 phase.
Schneider BL, Patton EE, Lanker S, Mendenhall MD, Wittenberg C, Futcher B, Tyers M. Schneider BL, et al. Nature. 1998 Sep 3;395(6697):86-9. doi: 10.1038/25774. Nature. 1998. PMID: 9738503
Regulation of hepatic energy metabolism and gluconeogenesis by BAD.
Giménez-Cassina A, Garcia-Haro L, Choi CS, Osundiji MA, Lane EA, Huang H, Yildirim MA, Szlyk B, Fisher JK, Polak K, Patton E, Wiwczar J, Godes M, Lee DH, Robertson K, Kim S, Kulkarni A, Distefano A, Samuel V, Cline G, Kim YB, Shulman GI, Danial NN. Giménez-Cassina A, et al. Cell Metab. 2014 Feb 4;19(2):272-84. doi: 10.1016/j.cmet.2013.12.001. Cell Metab. 2014. PMID: 24506868 Free PMC article.
A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators.
Szlyk B, Braun CR, Ljubicic S, Patton E, Bird GH, Osundiji MA, Matschinsky FM, Walensky LD, Danial NN. Szlyk B, et al. Nat Struct Mol Biol. 2014 Jan;21(1):36-42. doi: 10.1038/nsmb.2717. Epub 2013 Dec 8. Nat Struct Mol Biol. 2014. PMID: 24317490 Free PMC article.
Spontaneously occurring melanoma in animals and their relevance to human melanoma.
van der Weyden L, Brenn T, Patton EE, Wood GA, Adams DJ. van der Weyden L, et al. Among authors: patton ee. J Pathol. 2020 Jul 11:e5505. doi: 10.1002/path.5505. Online ahead of print. J Pathol. 2020. PMID: 32652526 Review.
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