Pau VP - Search Results

1

GCN4 enhances the stability of the pore domain of potassium channel KcsA.

Yuchi Z, Pau VP, Yang DS. Yuchi Z, et al. Among authors: pau vp. FEBS J. 2008 Dec;275(24):6228-36. doi: 10.1111/j.1742-4658.2008.06747.x. Epub 2008 Nov 7. FEBS J. 2008. PMID: 19016844 Free article.

2

Characterization of the C-terminal domain of a potassium channel from Streptomyces lividans (KcsA).

Pau VP, Zhu Y, Yuchi Z, Hoang QQ, Yang DS. Pau VP, et al. J Biol Chem. 2007 Oct 5;282(40):29163-9. doi: 10.1074/jbc.M703277200. Epub 2007 Aug 10. J Biol Chem. 2007. PMID: 17693406 Free article.

3

An engineered right-handed coiled coil domain imparts extreme thermostability to the KcsA channel.

Yuchi Z, Pau VP, Lu BX, Junop M, Yang DS. Yuchi Z, et al. Among authors: pau vp. FEBS J. 2009 Nov;276(21):6236-46. doi: 10.1111/j.1742-4658.2009.07327.x. Epub 2009 Sep 23. FEBS J. 2009. PMID: 19780836 Free article.

4

Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain.

Pau VP, Smith FJ, Taylor AB, Parfenova LV, Samakai E, Callaghan MM, Abarca-Heidemann K, Hart PJ, Rothberg BS. Pau VP, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17684-9. doi: 10.1073/pnas.1107229108. Epub 2011 Oct 12. Proc Natl Acad Sci U S A. 2011. PMID: 21997217 Free PMC article.

5

Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain.

Smith FJ, Pau VP, Cingolani G, Rothberg BS. Smith FJ, et al. Among authors: pau vp. Nat Commun. 2013;4:2621. doi: 10.1038/ncomms3621. Nat Commun. 2013. PMID: 24126388 Free article.

6

Crystal structure of a Ba(2+)-bound gating ring reveals elementary steps in RCK domain activation.

Smith FJ, Pau VP, Cingolani G, Rothberg BS. Smith FJ, et al. Among authors: pau vp. Structure. 2012 Dec 5;20(12):2038-47. doi: 10.1016/j.str.2012.09.014. Epub 2012 Oct 18. Structure. 2012. PMID: 23085076 Free PMC article.

7

Allosteric mechanism of Ca2+ activation and H+-inhibited gating of the MthK K+ channel.

Pau VP, Abarca-Heidemann K, Rothberg BS. Pau VP, et al. J Gen Physiol. 2010 May;135(5):509-26. doi: 10.1085/jgp.200910387. J Gen Physiol. 2010. PMID: 20421375 Free PMC article.

8

Crystal structure of an inactivated mutant mammalian voltage-gated K⁺ channel.

Pau V, Zhou Y, Ramu Y, Xu Y, Lu Z. Pau V, et al. Nat Struct Mol Biol. 2017 Oct;24(10):857-865. doi: 10.1038/nsmb.3457. Epub 2017 Aug 28. Nat Struct Mol Biol. 2017. PMID: 28846092 Free PMC article.

9

Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.

Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F. Chana CK, et al. J Med Chem. 2022 Oct 13;65(19):12725-12746. doi: 10.1021/acs.jmedchem.2c00509. Epub 2022 Sep 18. J Med Chem. 2022. PMID: 36117290 Free PMC article.

10

Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.

Szychowski J, Papp R, Dietrich E, Liu B, Vallée F, Leclaire ME, Fourtounis J, Martino G, Perryman AL, Pau V, Yin SY, Mader P, Roulston A, Truchon JF, Marshall CG, Diallo M, Duffy NM, Stocco R, Godbout C, Bonneau-Fortin A, Kryczka R, Bhaskaran V, Mao D, Orlicky S, Beaulieu P, Turcotte P, Kurinov I, Sicheri F, Mamane Y, Gallant M, Black WC. Szychowski J, et al. J Med Chem. 2022 Aug 11;65(15):10251-10284. doi: 10.1021/acs.jmedchem.2c00552. Epub 2022 Jul 26. J Med Chem. 2022. PMID: 35880755 Free PMC article.

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