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CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.
Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. Lo M, et al. Among authors: paul md. Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. Nat Commun. 2022. PMID: 35504891 Free PMC article.
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L; QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. Gupta M, et al. Among authors: paul md. bioRxiv. 2021 May 11:2021.05.10.443524. doi: 10.1101/2021.05.10.443524. Preprint. bioRxiv. 2021. PMID: 34013269 Free PMC article.
Interactions between Ligand-Bound EGFR and VEGFR2.
Paul MD, Hristova K. Paul MD, et al. J Mol Biol. 2021 Jun 25;433(13):167006. doi: 10.1016/j.jmb.2021.167006. Epub 2021 Apr 20. J Mol Biol. 2021. PMID: 33891904 Free PMC article.
Ligand bias in receptor tyrosine kinase signaling.
Karl K, Paul MD, Pasquale EB, Hristova K. Karl K, et al. Among authors: paul md. J Biol Chem. 2020 Dec 25;295(52):18494-18507. doi: 10.1074/jbc.REV120.015190. Epub 2020 Oct 29. J Biol Chem. 2020. PMID: 33122191 Free PMC article. Review.
61 results