Paul S - Search Results

1

Reduced levels of human apoE4 protein in an animal model of cognitive impairment.

Sullivan PM, Han B, Liu F, Mace BE, Ervin JF, Wu S, Koger D, Paul S, Bales KR. Sullivan PM, et al. Among authors: paul s. Neurobiol Aging. 2011 May;32(5):791-801. doi: 10.1016/j.neurobiolaging.2009.05.011. Epub 2009 Jul 4. Neurobiol Aging. 2011. PMID: 19577821

2

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Neurobiol Dis. 2002 Apr;9(3):305-18. doi: 10.1006/nbdi.2002.0483. Neurobiol Dis. 2002. PMID: 11950276

3

Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.

Nilsson LN, Arendash GW, Leighty RE, Costa DA, Low MA, Garcia MF, Cracciolo JR, Rojiani A, Wu X, Bales KR, Paul SM, Potter H. Nilsson LN, et al. Neurobiol Aging. 2004 Oct;25(9):1153-67. doi: 10.1016/j.neurobiolaging.2003.12.011. Neurobiol Aging. 2004. PMID: 15312961

4

Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms.

Costa DA, Cracchiolo JR, Bachstetter AD, Hughes TF, Bales KR, Paul SM, Mervis RF, Arendash GW, Potter H. Costa DA, et al. Neurobiol Aging. 2007 Jun;28(6):831-44. doi: 10.1016/j.neurobiolaging.2006.04.009. Epub 2006 May 26. Neurobiol Aging. 2007. PMID: 16730391

5

Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.

Zhao L, Gottesdiener AJ, Parmar M, Li M, Kaminsky SM, Chiuchiolo MJ, Sondhi D, Sullivan PM, Holtzman DM, Crystal RG, Paul SM. Zhao L, et al. Neurobiol Aging. 2016 Aug;44:159-172. doi: 10.1016/j.neurobiolaging.2016.04.020. Epub 2016 Apr 30. Neurobiol Aging. 2016. PMID: 27318144

6

Use of YFP to study amyloid-beta associated neurite alterations in live brain slices.

Brendza RP, Simmons K, Bales KR, Paul SM, Goldberg MP, Holtzman DM. Brendza RP, et al. Neurobiol Aging. 2003 Dec;24(8):1071-7. doi: 10.1016/j.neurobiolaging.2003.04.008. Neurobiol Aging. 2003. PMID: 14643378

7

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Fryer JD, et al. J Neurosci. 2005 Mar 16;25(11):2803-10. doi: 10.1523/JNEUROSCI.5170-04.2005. J Neurosci. 2005. PMID: 15772340 Free PMC article.

8

Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.

Bales KR, Liu F, Wu S, Lin S, Koger D, DeLong C, Hansen JC, Sullivan PM, Paul SM. Bales KR, et al. Among authors: paul sm. J Neurosci. 2009 May 27;29(21):6771-9. doi: 10.1523/JNEUROSCI.0887-09.2009. J Neurosci. 2009. PMID: 19474305 Free PMC article.

9

Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice.

Hunter JM, Cirrito JR, Restivo JL, Kinley RD, Sullivan PM, Holtzman DM, Koger D, Delong C, Lin S, Zhao L, Liu F, Bales K, Paul SM. Hunter JM, et al. Among authors: paul sm. Brain Res. 2012 Jul 27;1467:120-32. doi: 10.1016/j.brainres.2012.05.048. Epub 2012 Jun 5. Brain Res. 2012. PMID: 22682924

10

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.

Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Among authors: paul sm. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.

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