Paul SM - Search Results

1

Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.

Faraco G, Park L, Zhou P, Luo W, Paul SM, Anrather J, Iadecola C. Faraco G, et al. Among authors: paul sm. J Cereb Blood Flow Metab. 2016 Jan;36(1):241-52. doi: 10.1038/jcbfm.2015.79. J Cereb Blood Flow Metab. 2016. PMID: 25920959 Free PMC article.

2

Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.

Koizumi K, Hattori Y, Ahn SJ, Buendia I, Ciacciarelli A, Uekawa K, Wang G, Hiller A, Zhao L, Voss HU, Paul SM, Schaffer C, Park L, Iadecola C. Koizumi K, et al. Among authors: paul sm. Nat Commun. 2018 Sep 19;9(1):3816. doi: 10.1038/s41467-018-06301-2. Nat Commun. 2018. PMID: 30232327 Free PMC article.

3

Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.

Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul SM. Luo W, et al. Among authors: paul sm. Sci Rep. 2015 Jun 9;5:11161. doi: 10.1038/srep11161. Sci Rep. 2015. PMID: 26057852 Free PMC article.

4

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. Yuan P, et al. Among authors: paul sm. Neuron. 2016 May 18;90(4):724-39. doi: 10.1016/j.neuron.2016.05.003. Neuron. 2016. PMID: 27196974 Free PMC article.

5

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Wong MY, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF, Petsko GA, Holtzman DM, Paul SM, Luo W. Wong MY, et al. Among authors: paul sm. J Neuroinflammation. 2020 Jun 17;17(1):192. doi: 10.1186/s12974-020-01869-3. J Neuroinflammation. 2020. PMID: 32552741 Free PMC article.

6

Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression.

Rohe M, Synowitz M, Glass R, Paul SM, Nykjaer A, Willnow TE. Rohe M, et al. Among authors: paul sm. J Neurosci. 2009 Dec 9;29(49):15472-8. doi: 10.1523/JNEUROSCI.3960-09.2009. J Neurosci. 2009. PMID: 20007471 Free PMC article.

7

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. Yuan P, et al. Among authors: paul sm. Neuron. 2016 Oct 5;92(1):252-264. doi: 10.1016/j.neuron.2016.09.016. Neuron. 2016. PMID: 27710785 Free article. No abstract available.

8

Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.

Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, Hale J, Liu F, Hunter JM, Paul SM. Zhao L, et al. Among authors: paul sm. J Neurosci. 2009 Mar 18;29(11):3603-12. doi: 10.1523/JNEUROSCI.5302-08.2009. J Neurosci. 2009. PMID: 19295164 Free PMC article.

9

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

Fryer JD, Taylor JW, DeMattos RB, Bales KR, Paul SM, Parsadanian M, Holtzman DM. Fryer JD, et al. Among authors: paul sm. J Neurosci. 2003 Aug 27;23(21):7889-96. doi: 10.1523/JNEUROSCI.23-21-07889.2003. J Neurosci. 2003. PMID: 12944519 Free PMC article.

10

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS, Jordan WH, Brown DD, Hoffman WP, Holtzman DM, Bales KR, Gitter BD, May PC, Paul SM, DeMattos RB. Racke MM, et al. Among authors: paul sm. J Neurosci. 2005 Jan 19;25(3):629-36. doi: 10.1523/JNEUROSCI.4337-04.2005. J Neurosci. 2005. PMID: 15659599 Free PMC article.

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