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Cannabidiol ameliorates mitochondrial disease via PPARγ activation in preclinical models.
Puighermanal E, Luna-Sánchez M, Gella A, van der Walt G, Urpi A, Royo M, Tena-Morraja P, Appiah I, de Donato MH, Menardy F, Bianchi P, Esteve-Codina A, Rodríguez-Pascau L, Vergara C, Gómez-Pallarès M, Marsicano G, Bellocchio L, Martinell M, Sanz E, Jurado S, Soriano FX, Pizcueta P, Quintana A. Puighermanal E, et al. Among authors: tena morraja p. Nat Commun. 2024 Sep 4;15(1):7730. doi: 10.1038/s41467-024-51884-8. Nat Commun. 2024. PMID: 39231983 Free PMC article.
Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development.
Casellas-Díaz S, Larramona-Arcas R, Riqué-Pujol G, Tena-Morraja P, Müller-Sánchez C, Segarra-Mondejar M, Gavaldà-Navarro A, Villarroya F, Reina M, Martínez-Estrada OM, Soriano FX. Casellas-Díaz S, et al. Among authors: tena morraja p. EMBO Rep. 2021 Sep 6;22(9):e51954. doi: 10.15252/embr.202051954. Epub 2021 Jul 23. EMBO Rep. 2021. PMID: 34296790 Free PMC article.