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The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.
Richard AM, Huang R, Waidyanatha S, Shinn P, Collins BJ, Thillainadarajah I, Grulke CM, Williams AJ, Lougee RR, Judson RS, Houck KA, Shobair M, Yang C, Rathman JF, Yasgar A, Fitzpatrick SC, Simeonov A, Thomas RS, Crofton KM, Paules RS, Bucher JR, Austin CP, Kavlock RJ, Tice RR. Richard AM, et al. Among authors: paules rs. Chem Res Toxicol. 2021 Feb 15;34(2):189-216. doi: 10.1021/acs.chemrestox.0c00264. Epub 2020 Nov 3. Chem Res Toxicol. 2021. PMID: 33140634 Free PMC article. Review.
Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.
Xia M, Huang R, Shi Q, Boyd WA, Zhao J, Sun N, Rice JR, Dunlap PE, Hackstadt AJ, Bridge MF, Smith MV, Dai S, Zheng W, Chu PH, Gerhold D, Witt KL, DeVito M, Freedman JH, Austin CP, Houck KA, Thomas RS, Paules RS, Tice RR, Simeonov A. Xia M, et al. Among authors: paules rs. Environ Health Perspect. 2018 Jul 26;126(7):077010. doi: 10.1289/EHP2589. eCollection 2018 Jul. Environ Health Perspect. 2018. PMID: 30059008 Free PMC article.
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.
Mav D, Shah RR, Howard BE, Auerbach SS, Bushel PR, Collins JB, Gerhold DL, Judson RS, Karmaus AL, Maull EA, Mendrick DL, Merrick BA, Sipes NS, Svoboda D, Paules RS. Mav D, et al. Among authors: paules rs. PLoS One. 2018 Feb 20;13(2):e0191105. doi: 10.1371/journal.pone.0191105. eCollection 2018. PLoS One. 2018. PMID: 29462216 Free PMC article.
Evaluation of 5-day In Vivo Rat Liver and Kidney With High-throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes.
Gwinn WM, Auerbach SS, Parham F, Stout MD, Waidyanatha S, Mutlu E, Collins B, Paules RS, Merrick BA, Ferguson S, Ramaiahgari S, Bucher JR, Sparrow B, Toy H, Gorospe J, Machesky N, Shah RR, Balik-Meisner MR, Mav D, Phadke DP, Roberts G, DeVito MJ. Gwinn WM, et al. Among authors: paules rs. Toxicol Sci. 2020 Aug 1;176(2):343-354. doi: 10.1093/toxsci/kfaa081. Toxicol Sci. 2020. PMID: 32492150 Free PMC article.
The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling.
Ramaiahgari SC, Auerbach SS, Saddler TO, Rice JR, Dunlap PE, Sipes NS, DeVito MJ, Shah RR, Bushel PR, Merrick BA, Paules RS, Ferguson SS. Ramaiahgari SC, et al. Among authors: paules rs. Toxicol Sci. 2019 Jun 1;169(2):553-566. doi: 10.1093/toxsci/kfz065. Toxicol Sci. 2019. PMID: 30850835 Free PMC article.
127 results