Paulson HL - Search Results

1

Molecular medicine for the brain: silencing of disease genes with RNA interference.

Davidson BL, Paulson HL. Davidson BL, et al. Among authors: paulson hl. Lancet Neurol. 2004 Mar;3(3):145-9. doi: 10.1016/S1474-4422(04)00678-7. Lancet Neurol. 2004. PMID: 14980529 Review.

2

Allele-specific silencing of dominant disease genes.

Miller VM, Xia H, Marrs GL, Gouvion CM, Lee G, Davidson BL, Paulson HL. Miller VM, et al. Among authors: paulson hl. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7195-200. doi: 10.1073/pnas.1231012100. Epub 2003 Jun 2. Proc Natl Acad Sci U S A. 2003. PMID: 12782788 Free PMC article.

3

Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA.

Gonzalez-Alegre P, Miller VM, Davidson BL, Paulson HL. Gonzalez-Alegre P, et al. Among authors: paulson hl. Ann Neurol. 2003 Jun;53(6):781-7. doi: 10.1002/ana.10548. Ann Neurol. 2003. PMID: 12783425

4

Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles.

Miller VM, Gouvion CM, Davidson BL, Paulson HL. Miller VM, et al. Among authors: paulson hl. Nucleic Acids Res. 2004 Jan 30;32(2):661-8. doi: 10.1093/nar/gkh208. Print 2004. Nucleic Acids Res. 2004. PMID: 14754988 Free PMC article.

5

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL. Xia H, et al. Among authors: paulson hl. Nat Med. 2004 Aug;10(8):816-20. doi: 10.1038/nm1076. Epub 2004 Jul 4. Nat Med. 2004. PMID: 15235598

6

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.

Harper SQ, Staber PD, He X, Eliason SL, Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL, Davidson BL. Harper SQ, et al. Among authors: paulson hl. Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5820-5. doi: 10.1073/pnas.0501507102. Epub 2005 Apr 5. Proc Natl Acad Sci U S A. 2005. PMID: 15811941 Free PMC article.

7

Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia.

Gonzalez-Alegre P, Bode N, Davidson BL, Paulson HL. Gonzalez-Alegre P, et al. Among authors: paulson hl. J Neurosci. 2005 Nov 9;25(45):10502-9. doi: 10.1523/JNEUROSCI.3016-05.2005. J Neurosci. 2005. PMID: 16280588 Free PMC article.

8

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.

Rodríguez-Lebrón E, Costa Mdo C, Luna-Cancalon K, Peron TM, Fischer S, Boudreau RL, Davidson BL, Paulson HL. Rodríguez-Lebrón E, et al. Among authors: paulson hl. Mol Ther. 2013 Oct;21(10):1909-18. doi: 10.1038/mt.2013.152. Epub 2013 Jul 3. Mol Ther. 2013. PMID: 23820820 Free PMC article.

9

siRNA-mediated gene silencing in vitro and in vivo.

Xia H, Mao Q, Paulson HL, Davidson BL. Xia H, et al. Among authors: paulson hl. Nat Biotechnol. 2002 Oct;20(10):1006-10. doi: 10.1038/nbt739. Epub 2002 Sep 16. Nat Biotechnol. 2002. PMID: 12244328

10

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

Miller VM, Nelson RF, Gouvion CM, Williams A, Rodriguez-Lebron E, Harper SQ, Davidson BL, Rebagliati MR, Paulson HL. Miller VM, et al. Among authors: paulson hl. J Neurosci. 2005 Oct 5;25(40):9152-61. doi: 10.1523/JNEUROSCI.3001-05.2005. J Neurosci. 2005. PMID: 16207874 Free PMC article.

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