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Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Costa Mdo C, Luna-Cancalon K, Fischer S, Ashraf NS, Ouyang M, Dharia RM, Martin-Fishman L, Yang Y, Shakkottai VG, Davidson BL, Rodríguez-Lebrón E, Paulson HL. Costa Mdo C, et al. Among authors: paulson hl. Mol Ther. 2013 Oct;21(10):1898-908. doi: 10.1038/mt.2013.144. Epub 2013 Jun 14. Mol Ther. 2013. PMID: 23765441 Free PMC article.
CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.
Miller VM, Nelson RF, Gouvion CM, Williams A, Rodriguez-Lebron E, Harper SQ, Davidson BL, Rebagliati MR, Paulson HL. Miller VM, et al. Among authors: paulson hl. J Neurosci. 2005 Oct 5;25(40):9152-61. doi: 10.1523/JNEUROSCI.3001-05.2005. J Neurosci. 2005. PMID: 16207874 Free PMC article.
Allele-specific silencing of dominant disease genes.
Miller VM, Xia H, Marrs GL, Gouvion CM, Lee G, Davidson BL, Paulson HL. Miller VM, et al. Among authors: paulson hl. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7195-200. doi: 10.1073/pnas.1231012100. Epub 2003 Jun 2. Proc Natl Acad Sci U S A. 2003. PMID: 12782788 Free PMC article.
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.
Scaglione KM, Zavodszky E, Todi SV, Patury S, Xu P, Rodríguez-Lebrón E, Fischer S, Konen J, Djarmati A, Peng J, Gestwicki JE, Paulson HL. Scaglione KM, et al. Among authors: paulson hl. Mol Cell. 2011 Aug 19;43(4):599-612. doi: 10.1016/j.molcel.2011.05.036. Mol Cell. 2011. PMID: 21855799 Free PMC article.
261 results