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Siglecs and their roles in the immune system.
Crocker PR, Paulson JC, Varki A. Crocker PR, et al. Nat Rev Immunol. 2007 Apr;7(4):255-66. doi: 10.1038/nri2056. Nat Rev Immunol. 2007. PMID: 17380156 Review.
Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling.
Collins BE, Smith BA, Bengtson P, Paulson JC. Collins BE, et al. Nat Immunol. 2006 Feb;7(2):199-206. doi: 10.1038/ni1283. Epub 2005 Dec 20. Nat Immunol. 2006. PMID: 16369536
Siglec-mediated regulation of immune cell function in disease.
Macauley MS, Crocker PR, Paulson JC. Macauley MS, et al. Nat Rev Immunol. 2014 Oct;14(10):653-66. doi: 10.1038/nri3737. Epub 2014 Sep 19. Nat Rev Immunol. 2014. PMID: 25234143 Free PMC article. Review.
Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.
Tateno H, Li H, Schur MJ, Bovin N, Crocker PR, Wakarchuk WW, Paulson JC. Tateno H, et al. Mol Cell Biol. 2007 Aug;27(16):5699-710. doi: 10.1128/MCB.00383-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562860 Free PMC article.
Multivalent ligands for siglecs.
O'Reilly MK, Paulson JC. O'Reilly MK, et al. Methods Enzymol. 2010;478:343-63. doi: 10.1016/S0076-6879(10)78017-4. Methods Enzymol. 2010. PMID: 20816489 Free PMC article.
Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens.
Spiller F, Nycholat CM, Kikuchi C, Paulson JC, Macauley MS. Spiller F, et al. J Immunol. 2018 Feb 1;200(3):949-956. doi: 10.4049/jimmunol.1701257. Epub 2017 Dec 29. J Immunol. 2018. PMID: 29288201 Free PMC article.
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